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  1. Consumption of plant sterol (PS) esters lower low-density lipoprotein (LDL)-cholesterol levels by suppressing intestinal absorption of cholesterol. Commercially available PS are mainly esterified to omega-6 fa...

    Authors: Peter J. H. Jones, Isabelle Demonty, Yen-Ming Chan, Yael Herzog and Dori Pelled
    Citation: Lipids in Health and Disease 2007 6:28
    Content type: Research Published on:

  2. Patients with HIV are subject to development of HIV metabolic syndrome characterized by dyslipidemia, lipodystrophy and insulin resistance secondary to highly active antiretroviral therapy (HAART). Rosuvastati...

    Authors: Kevin W. Johns, Matthew T. Bennett and Gregory P. Bondy
    Citation: Lipids in Health and Disease 2007 6:27
    Content type: Short paper Published on:

  3. Lipoprotein(a) is an independent risk factor for Ischaemic Heart Disease (IHD) in the general population. There are conflicting reports in the extent of its association with IHD among subjects with Type 2 diab...

    Authors: Ali AlBahrani, Mohammed Alkindi, Eileen Marks, Said AlYahyaee and Alan Shenkin
    Citation: Lipids in Health and Disease 2007 6:26
    Content type: Research Published on:

  4. Milk and milk products are nutritious food items containing numerous essential nutrients, but in the western societies the consumption of milk has decreased partly due to claimed negative health effects. The c...

    Authors: Anna Haug, Arne T. Høstmark and Odd M. Harstad
    Citation: Lipids in Health and Disease 2007 6:25
    Content type: Review Published on:

  6. Mice with a deleted Gpihbp1 gene encoding glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPI-HBP1) develop severe chylomicronemia. We screened the coding regions of the human ho...

    Authors: Jian Wang and Robert A. Hegele
    Citation: Lipids in Health and Disease 2007 6:23
    Content type: Research Published on:

  7. We aimed to investigate if overweight and obese adults "close" to Mediterranean diet present better insulin, lipids profile and better pressure levels, compared to individuals close to a more Westernized diet.

    Authors: Natalia Tzima, Christos Pitsavos, Demosthenes B. Panagiotakos, John Skoumas, Antonis Zampelas, Christina Chrysohoou and Christodoulos Stefanadis
    Citation: Lipids in Health and Disease 2007 6:22
    Content type: Research Published on:

  9. Metabolic Syndrome, or Syndrome X, is characterized by a set of metabolic and lipid imbalances that greatly increases the risk of developing diabetes and cardiovascular disease. The syndrome is highly prevalen...

    Authors: Julius Oben, Ebangha Enonchong, Dieudonne Kuate, Dora Mbanya, Tiffany C. Thomas, DeWall J. Hildreth, Thomas D. Ingolia and Michael S. Tempesta
    Citation: Lipids in Health and Disease 2007 6:20
    Content type: Research Published on:

  10. ApolipoproteinA1(apoA1) is the major apoprotein constituent of high-density-lipoprotein(HDL). The relationship of apoA1 -75 bp(M1-) allele polymorphism with lipoprotein phenotype and cardiovascular diseae (CVD) r...

    Authors: Ali I. Albahrani, Jannete Usher J., Mohammed Alkindi, Eileen Marks, L. Ranganath and Said Al-yahyaee
    Citation: Lipids in Health and Disease 2007 6:19
    Content type: Research Published on:

  11. More than fifteen years ago it was discovered that intramyocellular triglyceride (imcTG) content in skeletal muscle is abnormally high in conditions of lipid oversupply (e.g. high fat feeding) and, later, obes...

    Authors: ZengKui Guo
    Citation: Lipids in Health and Disease 2007 6:18
    Content type: Review Published on:

  12. It has been observed that ras-transformed cell lines in culture have a higher phosphatidylcholine (PC) biosynthesis rate as well as higher PC-degradation rate (increased PC-turnover) than normal cells. In corr...

    Authors: Lenka A. Taylor, Jann Arends, Arwen K. Hodina, Clemens Unger and Ulrich Massing
    Citation: Lipids in Health and Disease 2007 6:17
    Content type: Research Published on:

  13. Exercise has been prescribed in the treatment and control of dyslipidemias and cholesterolemia, however, lipid responses to different training frequencies in hypercholesterolemic men have been inconsistent. We...

    Authors: Ricardo L. F. Guerra, Wagner L. Prado, Nádia C. Cheik, Fabiana P. Viana, João Paulo Botero, Regina C. Vendramini, Iracilda Z. Carlos, Elizeu A. Rossi and Ana R. Dâmaso
    Citation: Lipids in Health and Disease 2007 6:16
    Content type: Short paper Published on:

  15. Dietary supplement use is widespread in developed nations. In particular, patients who utilize mental health services also report frequent consumption of dietary supplements, often in relation to management of...

    Authors: Martin A Katzman, Leslie Jacobs, Madalyn Marcus, Monica Vermani and Alan C Logan
    Citation: Lipids in Health and Disease 2007 6:14
    Content type: Short paper Published on:

  16. Docosahexaenoic acid (22:6n-3, DHA) and n-6 docosapentaenoic acid (22:5n-6, DPAn-6) are highly unsaturated fatty acids (HUFA, ≥ 20 carbons, ≥ 3 double bonds) that differ by a single carbon-carbon double bond a...

    Authors: Ken D Stark, Sun-Young Lim and Norman Salem Jr
    Citation: Lipids in Health and Disease 2007 6:13
    Content type: Research Published on:

  17. To translate science into clinical practice we must first assess the quality of care that is being delivered. The resulting information about qualitative and quantitative parameters can then be assessed. Ultim...

    Authors: Allam Appa Rao and Gumpeny Ramachandra Sridhar
    Citation: Lipids in Health and Disease 2007 6:12
    Content type: Commentary Published on:

  19. The effects of 24(S),25-epoxycholesterol (24,25EC) on aspects of cholesterol homeostasis is well-documented. When added to cells, 24,25EC decreases cholesterol synthesis and up-regulates cholesterol efflux genes,...

    Authors: Jenny Wong, Carmel M Quinn and Andrew J Brown
    Citation: Lipids in Health and Disease 2007 6:10
    Content type: Research Published on:

  20. Several trials from different populations have reported that non-high density lipoprotein cholesterol (non-HDL-C) has more predictive power than low-density lipoprotein cholesterol (LDL-C) in detecting coronar...

    Authors: Nasser M Al-Daghri, Omar S Al-Attas and Khalid Al-Rubeaan
    Citation: Lipids in Health and Disease 2007 6:9
    Content type: Research Published on:

  21. A single session of exercise has been reported to reduce fasting and postprandial triacylglycerol concentrations on the subsequent day. It is possible that exercise also reduces chylomicron particle number, wh...

    Authors: Anthony P James, Karin Slivkoff-Clark and John CL Mamo
    Citation: Lipids in Health and Disease 2007 6:8
    Content type: Research Published on:

  22. Statin-related skeletal muscle disorders range from benign myalgias – such as non-specific muscle aches or joint pains without elevated serum creatinine kinase (CK) concentration – to true myositis with >10-fo...

    Authors: Jisun Oh, Matthew R Ban, Brooke A Miskie, Rebecca L Pollex and Robert A Hegele
    Citation: Lipids in Health and Disease 2007 6:7
    Content type: Research Published on:

  23. Feeding oxidized fats causes activation of peroxisome proliferator-activated receptor α (PPARα) in the liver of rats. However, whether feeding oxidized fat during pregnancy also results in activation of PPARα ...

    Authors: Robert Ringseis, Anke Gutgesell, Corinna Dathe, Corinna Brandsch and Klaus Eder
    Citation: Lipids in Health and Disease 2007 6:6
    Content type: Short paper Published on:

  25. Obesity is generally linked to complications in lipid metabolism and oxidative stress. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a prop...

    Authors: Julius E Oben, Damaris Mandob Enyegue, Gilles I Fomekong, Yves B Soukontoua and Gabriel A Agbor
    Citation: Lipids in Health and Disease 2007 6:4
    Content type: Research Published on:

  27. Mice that lack acyl CoA:diacylglycerol acyltransferase (Dgat1-/- mice) are reported to have a reduced body fat content and improved glucose tolerance and insulin sensitivity. Studies so far have focussed on male ...

    Authors: Steven JY Wang, Claire Cornick, Jacqueline O'Dowd, Michael A Cawthorne and Jonathan R S Arch
    Citation: Lipids in Health and Disease 2007 6:2
    Content type: Research Published on:

  28. Cardiovascular disease (CVD) is the Nation's leading killer for both men and women among all racial and ethnic groups. Development and progression of CVD is linked to the presence of risk factors such as hyper...

    Authors: Danik M Martirosyan, Lidia A Miroshnichenko, Svetlana N Kulakova, Ala V Pogojeva and Vladimir I Zoloedov
    Citation: Lipids in Health and Disease 2007 6:1
    Content type: Research Published on:

  29. Severe combined hyperlipidaemia has occasionally been associated with infiltration of tissues in addition to arteries and the skin. We report a woman with Type 2 diabetes mellitus (DM) and severe combined hype...

    Authors: Rachel A Davey, Niall C Tebbutt, Jenny M Favaloro, David N O'Neal, Derek Rae, Jeffrey D Zajac and James D Best
    Citation: Lipids in Health and Disease 2006 5:29
    Content type: Short paper Published on:

  30. Alzheimer's disease and type 2 diabetes mellitus tend to occur together. We sought to identify protein(s) common to both conditions that could suggest a possible unifying pathogenic role. Using human neuronal ...

    Authors: Appa Rao Allam, Gumpeny Ramachandra Sridhar, Hanuman Thota, Changalasetty Suresh Babu, Akula Siva Prasad and Ch Divakar
    Citation: Lipids in Health and Disease 2006 5:28
    Content type: Short paper Published on:

  31. The lipodystrophic syndrome (LD) is a disorder resulting from selective damage of adipose tissue by antiretroviral drugs included in therapy controlling human-immunodeficiency-virus-1. In the therapy cocktail ...

    Authors: Christel Gentil, Sébastien Le Jan, Josette Philippe, Jacques Leibowitch, Pierre Sonigo, Stéphane Germain and France Piétri-Rouxel
    Citation: Lipids in Health and Disease 2006 5:27
    Content type: Research Published on:

  32. The glycosphingolipid sulfatide has previously been found in several mammalian tissues, but information on the uptake of exogenously administered sulfatide in different organs in vivo is limited. In pancreatic be...

    Authors: Maria Blomqvist, Thomas Osterbye, Jan-Eric MÃ¥nsson, Karsten Buschard and Pam Fredman
    Citation: Lipids in Health and Disease 2006 5:26
    Content type: Research Published on:

  33. It has been shown that calcifying vesicles play an important role in aortic calcification and that cholesterol content in the isolated vesicle fraction is increased when rabbits are fed supplemental cholestero...

    Authors: Howard HT Hsu and Nathan C Culley
    Citation: Lipids in Health and Disease 2006 5:25
    Content type: Research Published on:

  34. Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investig...

    Authors: Julius Oben, Dieudonne Kuate, Gabriel Agbor, Claudia Momo and Xavio Talla
    Citation: Lipids in Health and Disease 2006 5:24
    Content type: Research Published on:

  35. Triacylglyerol-rich very low density lipoprotein (VLDL) particles are the primary carriers of fatty acids in the circulation and as such serve as a rich energy source for peripheral tissues. Receptor-mediated ...

    Authors: Larissa C Wilsie, Amanda M Gonzales and Robert A Orlando
    Citation: Lipids in Health and Disease 2006 5:23
    Content type: Research Published on:

  36. HMG-CoA reductase and the LDL receptor are ubiquitously expressed in major tissues. Since the liver plays a major role in regulating circulating LDL, it is usually of interest to measure the effects of drug or...

    Authors: Dimple Aggarwal, Hedley C Freake, Ghada A Soliman, Amrita Dutta and Maria-Luz Fernandez
    Citation: Lipids in Health and Disease 2006 5:22
    Content type: Short paper Published on:

  37. Arylsulfatase A (ASA)-deficient mice are a model for the lysosomal storage disorder metachromatic leukodystrophy. This lipidosis is characterised by the lysosomal accumulation of the sphingolipid sulfatide. St...

    Authors: S Franken, D Wittke, JE Mansson, R D'Hooge, PP De Deyn, R Lüllmann-Rauch, U Matzner and V Gieselmann
    Citation: Lipids in Health and Disease 2006 5:21
    Content type: Research Published on:

  38. Adaptation of assays on dried blood has advantages of ease of collection, transportation, minimal invasiveness and requirement of small volume. A method for extraction and estimation of triglyceride from blood...

    Authors: Rizwana Quraishi, Ramakrishnan Lakshmy, Dorairaj Prabhakaran, Ashok Kumar Mukhopadhyay and Bansilal Jailkhani
    Citation: Lipids in Health and Disease 2006 5:20
    Content type: Short paper Published on:

  39. Lipoprotein Lipase (LPL), a key enzyme in lipid metabolism, catalyzes the hydrolysis of triglycerides (TG) from TG-rich lipoproteins, and serves a bridging function that enhances the cellular uptake of lipopro...

    Authors: Shu-Fen Wung, Medha V Kulkarni, Clive R Pullinger, Mary J Malloy, John P Kane and Bradley E Aouizerat
    Citation: Lipids in Health and Disease 2006 5:19
    Content type: Research Published on:

  42. Vascular calcification is implicated in myocardial infarction, instability and rigidity of the aortic wall, and bioprosthetic failures. Although an increase in the calcium (Ca) content in atherogenic diets has...

    Authors: Howard HT Hsu and Nathan C Culley
    Citation: Lipids in Health and Disease 2006 5:16
    Content type: Research Published on:

  43. Tegaserod is effective in treating IBS patients with constipation, and does not alter gallbladder motility in healthy individuals or in patients with IBS. However, it is not known if tegaserod affects the bili...

    Authors: Ronald Mathison, Eldon Shaffer, Hans-Juergen Pfannkuche and David Earnest
    Citation: Lipids in Health and Disease 2006 5:15
    Content type: Research Published on:

  44. Hyperlipidemia is a major risk factor in etiology of cardiovascular disease. Previous studies have shown association between vegetarian diet and low total serum cholesterol as well as LDL-cholesterol which is ...

    Authors: Olugbenga Adebawo, Bamidele Salau, Esther Ezima, Olamilekan Oyefuga, Emmanuel Ajani, Gbolahan Idowu, Adekunle Famodu and Odutola Osilesi
    Citation: Lipids in Health and Disease 2006 5:14
    Content type: Research Published on:

  46. A new water-based topical formulation is presented that aims at providing good penetration properties for both lipophilic and hydrophilic drugs with as small a disturbance of the skin barrier function as possi...

    Authors: Mats Silvander, Lovisa Ringstad, Ruby Ghadially and Thomas Sköld
    Citation: Lipids in Health and Disease 2006 5:12
    Content type: Research Published on:

  47. Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping...

    Authors: Kirsten J Ward, Sian Ellard, Chittaranjan S Yajnik, Timothy M Frayling, Andrew T Hattersley, Prathyusha NS Venigalla and Giriraj R Chandak
    Citation: Lipids in Health and Disease 2006 5:11
    Content type: Research Published on:

  48. Herein, we expand our previous work on the effects of long chain polyunsaturated fatty acids (LC-PUFA) on the murine hepatic transcriptome using novel statistical and bioinformatic approaches for evaluating mi...

    Authors: Alvin Berger, Matthew A Roberts and Bruce Hoff
    Citation: Lipids in Health and Disease 2006 5:10
    Content type: Research Published on:

  49. previous studies have indicated on association between shift work and lipid profile disturbances. Lipid profile disturbances could be due to internal desynchronization. The aim of this study was to analyze whe...

    Authors: Masoumeh Ghiasvand, Ramin Heshmat, Reza Golpira, Vahid Haghpanah, Ali Soleimani, Payman Shoushtarizadeh, Seyed Mohammad Tavangar and Bagher Larijani
    Citation: Lipids in Health and Disease 2006 5:9
    Content type: Research Published on:

  50. The Friedewald formula (LDL-F) for the estimation of low-density lipoprotein (LDL) cholesterol concentrations is the most often used formula in clinical trials and clinical practice. However, much concern has ...

    Authors: Irene Gazi, Vasilis Tsimihodimos, Theodosios D Filippatos, Vasilios G Saougos, Eleni T Bairaktari, Alexandros D Tselepis and Moses Elisaf
    Citation: Lipids in Health and Disease 2006 5:8
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X