Fig. 3From: The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databasesThe metabolites and genes involved in SM metabolism. ASAHs catalyze ceramide to sphingosine, which is phosphorylated by SPHK to produce S1P. S1P can bind to S1PRs on the cell surface to regulate cell function or be degraded by SGPL1Back to article page