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Table 7 Multivariate regression analysis of the effect of HDL-C on BMD in different gender populations

From: Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study

 

Linear regression

Break point (K)

< K

> K

LLR test

β (95%CI)

 

β (95%CI)

β (95%CI)

P

Male

     

Age (year)

     

<= 45

-7.47 (-13.22, -1.72)

0.86

-55.88 (-101.14, -10.62)

-6.05 (-11.94, -0.15)

0.034*

> 45

-7.45 (-11.13, -3.77)

1.12

-24.74 (-33.76, -15.72)

-3.97 (-8.00, 0.06)

< 0.001***

BMI (kg/m2)

     

<= 24

-6.36 (-12.18, -0.53)

1.28

-15.56 (-25.64, -5.49)

-2.83 (-9.45, 3.79)

0.028*

> 24, <= 28

-10.51 (-14.54, -6.47)

1.09

-24.60 (-35.10, -14.11)

-7.43 (-11.98, -2.87)

0.004**

> 28

-12.14 (-19.18, -5.10)

1.45

-9.64 (-17.73, -1.55)

-23.58 (-43.14, -4.02)

0.217

Female

     

Age (year)

     

<= 45

-2.69 (-12.65, 7.27)

1.64

-8.44 (-20.42, 3.53)

5.37 (-8.27, 19.02)

0.087

> 45

-1.30 (-6.46, 3.86)

1.35

-13.62 (-23.71, -3.53)

2.85 (-3.07, 8.79)

0.005**

BMI (kg/m2)

     

<= 24

-3.23 (-8.38, 1.91)

1.34

-16.55 (-27.87, -5.24)

0.01 (-5.69, 5.70)

0.009**

> 24, <= 28

-8.47 (-15.29, -1.64)

1.83

-5.69 (-13.06, 1.67)

-30.91 (-54.53, -7.28)

0.050

> 28

-1.20 (-15.07, 12.66)

1.02

-52.76 (-139.48, 33.96)

0.21 (-13.84, 14.28)

0.226

  1. Each stratification was adjusted for all factors (age, nationality, marital status, high, weight, BMI, DBP, SBP, TC, LDL-C, TG, TP, Alb, Hb, globulin, TB, direct bilirubin, ALT, AST, transglutaminase, ALP, FBG, serum calcium, serum creatinine, UA, serum phosphorus, and GH), except for the stratification factor itself
  2. *P < 0.05, **P < 0.01, ***P < 0.001