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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Dysregulated lipid metabolism is associated with kidney allograft fibrosis

Fig. 4

Pathological staining and transcriptome profiling analysis in rat model of kidney transplantation. (a) HE and Masson staining showed extensive mononuclear cell infiltration and an increased fibrosis area, respectively, in the allograft group. (b) The transcript per million (TPM) distribution shows the eligible transcriptome data between the allograft group (fibrosis) and the syngeneic allograft group (normal). (c) Volcano plot showing 1136 upregulated genes and 881 downregulated genes compared to those in the syngeneic allograft group. (d) GO analysis of the 1136 up regulated DEGs. (e) GO analysis of the 881 downregulated DEGs. (f) WikiPathways enrichment analysis of all 2017 DEGs

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