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Table 2 General characteristics of participants according to the history of hysterectomy

From: Association of hysterectomy with nonalcoholic fatty liver disease among US women

 

Without hysterectomy

n = 2205

With hysterectomy

n = 663

P-value

Age, years

48.0 (46.6, 49.4)

62.8 (61.3, 64.3)

< 0.001

Race/ethnicity, %

  

< 0.001

 NH-White

61.6 (56.1, 66.8)

69.3 (61.5, 76.3)

 

 NH-Black

12.2 (9.5, 15.6)

11.4 (7.4, 17.0)

 

 NH-Asian

7.1 (5.1, 9.8)

3.0 (1.7, 5.2)

 

 Hispanic

15.7 (12.8, 19.2)

11.0 (7.8, 15.3)

 

 Other

3.3 (2.5, 4.4)

5.3 (3.2, 8.8)

 

BMI, kg/m2

29.4 (28.7, 30.1)

30.6 (29.8, 31.4)

0.008

WC, cm

96.9 (95.3, 98.5)

101.5 (99.9, 103.2)

< 0.001

Bilateral oophorectomy, %

0.4 (0.2, 1.1)

54.1 (49.5, 58.7)

< 0.001

Female hormone use, %

12.7 (10.5, 15.4)

45.9 (40.2, 51.7)

< 0.001

Diabetes mellitus, %

10.8 (9.3, 12.5)

24.0 (19.7, 28.9)

< 0.001

Hyperlipidemia, %

66.9 (62.8, 70.7)

80.0 (76.2, 83.4)

< 0.001

Smoking status, %

  

0.344

 Never

68.2 (65.0, 71.3)

63.4 (57.6, 68.9)

 

 Former

21.0 (18.3, 24.0)

23.3 (18.8, 28.5)

 

 Current

10.8 (8.6, 13.5)

13.3 (9.5, 18.4)

 

NAFLD, %

27.7 (25.0, 30.7)

42.8 (37.6, 48.2)

< 0.001

NAFLD with CSF, %

3.4 (2.3, 4.9)

5.4 (3.0, 9.6)

0.088

CAP, dB/m

249.9 (245.8, 254.0)

272.0 (266.5, 277.6)

< 0.001

LSM, kPa

5.2 (5.0, 5.4)

5.6 (5.3, 6.0)

0.020

Laboratory features

   

 ALT, IU/L

17.7 (17.1, 18.2)

20.0 (17.8, 22.3)

0.076

 AST, IU/L

19.2 (18.6, 19.8)

20.5 (19.5, 21.6)

0.058

 Total bilirubin, mg/dL

0.40 (0.39, 0.42)

0.39 (0.36, 0.41)

0.314

 Albumin, g/dL

4.04 (4.01, 4.06)

4.01 (3.98, 4.04)

0.166

 Total cholesterol, mg/dL

191.1 (188.4, 193.8)

201.2 (195.1, 207.3)

0.001

 HDL-cholesterol, mg/dL

59.1 (58.2, 59.9)

60.0 (56.9, 63.2)

0.555

 Triglyceride, mg/dL

119.4 (115.5, 123.2)

144.7 (134.4, 155.0)

< 0.001

 HbA1c, %

5.61 (5.57, 5.65)

5.90 (5.78, 6.01)

< 0.001

 Platelet count, 109/L

259 (254, 265)

255 (247, 263)

0.309

 HS-CRP, mg/L

4.07 (3.57, 4.58)

4.51 (3.76, 5.26)

0.237

  1. Data are expressed as weighted means (95% CI) for continuous variables and as weighted proportions (95% CI) for categorical variables. Differences by groups were assessed through Survey-weighted linear regression and Chi-square test
  2. Abbreviations: NH, non-Hispanic; BMI, body mass index; WC, waist circumference; NAFLD, nonalcoholic fatty liver disease; CSF, clinically significant fibrosis; CAP, controlled attenuation parameter; LSM, liver stiffness measure. ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL, high-density lipoprotein; HbA1c: Hemoglobin A1c; HS-CRP, high-sensitive C-reactive protein
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Lipids in Health and Disease

ISSN: 1476-511X