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Table 1 General characteristics of overall participants and according to the presence of NAFLD, NHANES 2017-March 2020

From: Association of hysterectomy with nonalcoholic fatty liver disease among US women

 

Overall

n = 2868

Non-NAFLD

n = 1931

NAFLD

n = 937

P-value

Age, years

51.3 (50.0, 52.6)

49.4 (48.1, 50.7)

55.4 (53.8, 57.0)

< 0.001

Race/ethnicity, %

   

0.401

 NH-White

63.3 (57.7, 68.5)

63.4 (57.8, 68.7)

63.0 (55.4, 70.0)

 

 NH-Black

12.0 (9.1, 15.8)

12.4 (9.4, 16.2)

11.2 (8.0, 15.5)

 

 NH-Asian

6.2 (4.4, 8.7)

6.6 (4.8, 9.0)

5.3 (3.3, 8.4)

 

 Hispanic

14.7 (12.0, 17.9)

14.1 (11.4, 17.3)

16.0 (12.1, 20.9)

 

 other

3.8 (2.8, 5.0)

3.5 (2.3, 5.2)

4.5 (3.0, 6.6)

 

BMI, kg/m2

29.7 (29.0, 30.3)

27.3 (26.7, 27.8)

35.0 (34.0, 35.9)

< 0.001

WC, cm

97.9 (96.4, 99.4)

92.1 (90.8, 93.4)

110.8 (108.7, 112.9)

< 0.001

Hysterectomy, %

22.1 (19.7, 24.7)

18.3 (16.3, 20.4)

30.4 (25.9, 35.4)

< 0.001

Bilateral oophorectomy, %

12.3 (10.6, 14.2)

10.3 (8.7, 12.2)

16.5 (12.7, 21.2)

0.002

Female hormone use, %

20.1 (17.9, 22.5)

18.3 (15.7, 21.3)

23.9 (20.4, 27.7)

0.009

Diabetes mellitus, %

13.7 (12.2, 15.4)

6.3 (5.2, 7.6)

30.2 (26.5, 34.2)

< 0.001

Hyperlipidemia, %

69.8 (66.5, 72.8)

63.5 (59.7, 67.1)

83.6 (80.1, 86.6)

< 0.001

Smoking status, %

   

0.784

 Never

67.2 (64.6, 69.6)

67.5 (66.3, 69.7)

66.3 (60.7, 71.5)

 

 Former

21.5 (19.1, 24.1)

21.6 (19.7, 23.6)

21.4 (16.0, 27.9)

 

 Current

11.3 (9.5, 13.5)

10.9 (9.2, 12.8)

12.3 (8.6, 17.4)

 

CAP, dB/m

254.8 (251.1, 258.4)

223.0 (220.4, 225.6)

325.4 (322.8, 328.0)

< 0.001

LSM, kPa

5.3 (5.1, 5.5)

4.7 (4.6, 4.9)

6.5 (6.0, 6.9)

< 0.001

Laboratory features

    

 ALT, IU/L

18.2 (17.6, 18.7)

16.5 (15.5, 17.5)

21.9 (20.9, 22.9)

< 0.001

 AST, IU/L

19.5 (19.0, 19.9)

18.9 (18.3, 19.5)

20.6 (19.9, 21.3)

0.002

 Total bilirubin, mg/dL

0.40 (0.39, 0.41)

0.41 (0.39, 0.42)

0.38 (0.37, 0.40)

0.061

 Albumin, g/dl

4.03 (4.01, 4.05)

4.06 (4.03, 4.08)

3.98 (3.95, 4.01)

0.002

 Total cholesterol, mg/dl

193.3 (190.4, 196.2)

192.3 (189.2, 195.5)

195.5 (191.3, 199.6)

0.146

 HDL-cholesterol, mg/dl

59.3 (58.3, 60.3)

62.3 (61.2, 63.5)

52.6 (51.4, 53.9)

< 0.001

 Triglyceride, mg/dl

124.9 (120.1, 129.3)

107.7 (103.4, 111.3)

162.8 (156.1, 169.5)

< 0.001

 HbA1c, %

5.67 (5.64, 5.71)

5.48 (5.46, 5.51)

6.09 (6.01, 6.18)

< 0.001

 Platelet count, 109/L

258 (253, 264)

254 (249, 259)

268 (261, 276)

< 0.001

 HS-CRP, mg/L

4.17 (3.68, 4.66)

3.41 (2.86, 3.97)

5.83 (5.19, 6.47)

< 0.001

  1. Data are weighted means (95% CI) for continuous variables and weighted proportions (95% CI) for categorical variables. Differences by groups were assessed through Survey-weighted linear regression and Chi-square test
  2. Abbreviations: NAFLD, nonalcoholic fatty liver disease; NHANES, National Health and Nutrition Examination Survey; NH, non-Hispanic; BMI, body mass index; WC, waist circumference; CAP, controlled attenuation parameter; LSM, liver stiffness measure. ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL, high-density lipoprotein; HbA1c: Hemoglobin A1c; HS-CRP, high-sensitive C-reactive protein
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Lipids in Health and Disease

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