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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: A novel lipid metabolism-based risk model associated with immunosuppressive mechanisms in diffuse large B-cell lymphoma

Fig. 6

Identification of Immune-Independent Hub Genes. (A) Correlation analysis of the 16 genes associated with the T-cell receptor signaling pathway across multiple datasets, including GSE181063, GSE10846 R-CHOP, GSE10846 CHOP, GSE11318, and NCICCR. (B) Examination of the correlation between the 16 genes and natural killer cell-mediated cytotoxicity in the same datasets as in (A). (C) Pearson correlation analysis illustrating the relationship between the expression of the 5 lipid metabolism/survival-related genes and the levels of infiltrating immune cells in the GSE181063 dataset. (D) Box plots displaying the expression patterns of the 5 genes analyzed using the GEPIA website. DLBCL patients are represented in red, while normal controls are depicted in grey. *P < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X