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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: A novel lipid metabolism-based risk model associated with immunosuppressive mechanisms in diffuse large B-cell lymphoma

Fig. 5

Functional enrichment examination of the lipid metabolism-derived risk level approach. (A) GSVA examination of the biological pathways within the high- and low-risk score groups from the GSE181063, GSE10846 R-CHOP, GSE10846 CHOP, GSE11318, and NCICCR datasets. Orange and blue indicates the activation and inhibition of biological pathways, respectively. (B) GSEA indicates a significant increase in natural killer cell-mediated cytotoxicity, and T-cell receptor signaling pathways in the GSE181063 cohort. (C) Estimate score, immunity score, and stromal score across the high- and low-risk groups from the GSE181063 cohort. (D) ssGSEA comparison of the scores from various infiltrating immunity cells across DLBCL patients with high- and low-risk scores from the GSE181063 cohort. ***P < 0.001; **P < 0.01; *P < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X