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Table 1 Baseline features after matching

From: High lipoprotein(a) concentration is associated with moyamoya disease

Characteristics

MMD group

Control group

P value

Total number (n)

1012

2024

-

Demographic data

   

Male, n (%)

520 (51.5)

1041 (51.4)

0.980‡

Age

51.0 (45.0–60.0)

51.0 (45.0–60.0)

0.981†

BMI (kg/m2)

23.4 (22.4–24.5)

23.5 (21.9–25.3)

0.078†

Smoking status, n (%)

137 (13.5)

271 (13.4)

0.910‡

Alcohol consumption status, n (%)

124 (12.6)

244 (12.1)

0.875‡

SBP (mmHg)

131 (120–145)

128 (117–144)

0.001*†

DBP (mmHg)

78 (70–84)

78 (71–86)

0.017*†

Medical history

   

Coronary heart disease, n (%)

35 (3.5)

70 (3.5)

1.000‡

Hypertension, n (%)

402 (39.7)

807 (39.9)

0.937‡

Diabetes mellitus, n (%)

145 (14.3)

349 (17.2)

0.040*‡

Laboratory values

   

Lp(a) (mg/dL)

18.5 (9.6–37.8)

14.9 (7.8–30.5)

< 0.001*†

Albumin (g/L)

40.9 (37.7–43.0)

41.6 (38.5–44.1)

< 0.001*†

Platelet count (10^9/L)

212.0 (177.0-247.0)

216.0 (179.0-257.0)

0.038*†

Glucose (mmol/L)

5.70 (4.99–6.65)

5.54 (4.87–6.60)

0.053†

Fibrinogen (g/L)

2.62 (2.28–2.98)

2.62 (2.29–3.05)

0.435†

TG (mmol/L)

1.42 (1.04–1.84)

1.42 (0.99–2.16)

0.130†

Lymphocyte count (10^9/L)

1.71 (1.23–2.05)

1.74 (1.36–2.15)

< 0.001*†

HDL-C (mmol/L)

1.09 (0.88–1.36)

1.17 (0.96–1.43)

< 0.001*†

LDL-C (mmol/L)

2.76 (2.22–3.05)

2.81 (2.26–3.35)

< 0.001*†

Uric acid (µmol/L)

307.9 (248.9–370.0)

322.4 (263.6-394.2)

< 0.001*†

Neutrophil count (10^9/L)

4.22 (3.52–6.43)

3.79 (2.97–4.95)

< 0.001*†

C-reactive protein (mg/L)

6.49 (3.24–15.25)

7.34 (3.81–14.19)

0.162†

Apolipoprotein A-I (g/L)

1.12 (0.96–1.28)

1.18 (1.00-1.43)

< 0.001*†

Apolipoprotein B (g/L)

0.87 (0.72-1.00)

0.89 (0.73–1.08)

0.001*†

TC (mmol/L)

4.61 (3.99–5.04)

4.82 (4.11–5.51)

< 0.001*†

HCY (µmol/L)

11.85 (10.05–14.13)

11.91 (9.96–14.25)

0.984†

eGFR (mL/min/1.73 m²)

95.4 (78.1-112.4)

92.7 (77.4-110.4)

0.080†

Creatinine (µmol/L)

65.69 (53.95–78.39)

67.30 (55.94–79.48)

0.005*†

Drugs

   

Statin, n(%)

515 (50.9)

524 (25.9)

< 0.001*‡

  1. Data are represented as the median (interquartile range) for variables and as n (%) for categorical variables
  2. *P < 0.05
  3. †Mann‒Whitney U test
  4. ‡Chi-square test