From: High lipoprotein(a) concentration is associated with moyamoya disease
Characteristics | MMD group | Control group | P value |
---|---|---|---|
Total number (n) | 1012 | 2024 | - |
Demographic data | |||
Male, n (%) | 520 (51.5) | 1041 (51.4) | 0.980‡ |
Age | 51.0 (45.0–60.0) | 51.0 (45.0–60.0) | 0.981† |
BMI (kg/m2) | 23.4 (22.4–24.5) | 23.5 (21.9–25.3) | 0.078† |
Smoking status, n (%) | 137 (13.5) | 271 (13.4) | 0.910‡ |
Alcohol consumption status, n (%) | 124 (12.6) | 244 (12.1) | 0.875‡ |
SBP (mmHg) | 131 (120–145) | 128 (117–144) | 0.001*† |
DBP (mmHg) | 78 (70–84) | 78 (71–86) | 0.017*† |
Medical history | |||
Coronary heart disease, n (%) | 35 (3.5) | 70 (3.5) | 1.000‡ |
Hypertension, n (%) | 402 (39.7) | 807 (39.9) | 0.937‡ |
Diabetes mellitus, n (%) | 145 (14.3) | 349 (17.2) | 0.040*‡ |
Laboratory values | |||
Lp(a) (mg/dL) | 18.5 (9.6–37.8) | 14.9 (7.8–30.5) | < 0.001*† |
Albumin (g/L) | 40.9 (37.7–43.0) | 41.6 (38.5–44.1) | < 0.001*† |
Platelet count (10^9/L) | 212.0 (177.0-247.0) | 216.0 (179.0-257.0) | 0.038*† |
Glucose (mmol/L) | 5.70 (4.99–6.65) | 5.54 (4.87–6.60) | 0.053† |
Fibrinogen (g/L) | 2.62 (2.28–2.98) | 2.62 (2.29–3.05) | 0.435† |
TG (mmol/L) | 1.42 (1.04–1.84) | 1.42 (0.99–2.16) | 0.130† |
Lymphocyte count (10^9/L) | 1.71 (1.23–2.05) | 1.74 (1.36–2.15) | < 0.001*† |
HDL-C (mmol/L) | 1.09 (0.88–1.36) | 1.17 (0.96–1.43) | < 0.001*† |
LDL-C (mmol/L) | 2.76 (2.22–3.05) | 2.81 (2.26–3.35) | < 0.001*† |
Uric acid (µmol/L) | 307.9 (248.9–370.0) | 322.4 (263.6-394.2) | < 0.001*† |
Neutrophil count (10^9/L) | 4.22 (3.52–6.43) | 3.79 (2.97–4.95) | < 0.001*† |
C-reactive protein (mg/L) | 6.49 (3.24–15.25) | 7.34 (3.81–14.19) | 0.162† |
Apolipoprotein A-I (g/L) | 1.12 (0.96–1.28) | 1.18 (1.00-1.43) | < 0.001*† |
Apolipoprotein B (g/L) | 0.87 (0.72-1.00) | 0.89 (0.73–1.08) | 0.001*† |
TC (mmol/L) | 4.61 (3.99–5.04) | 4.82 (4.11–5.51) | < 0.001*† |
HCY (µmol/L) | 11.85 (10.05–14.13) | 11.91 (9.96–14.25) | 0.984† |
eGFR (mL/min/1.73 m²) | 95.4 (78.1-112.4) | 92.7 (77.4-110.4) | 0.080† |
Creatinine (µmol/L) | 65.69 (53.95–78.39) | 67.30 (55.94–79.48) | 0.005*† |
Drugs | |||
Statin, n(%) | 515 (50.9) | 524 (25.9) | < 0.001*‡ |