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Table 2 Association of AIP level at baseline with the incidence of DKD and DR

From: Impact of baseline and trajectory of the atherogenic index of plasma on incident diabetic kidney disease and retinopathy in participants with type 2 diabetes: a longitudinal cohort study

  

Model 1

Model 2

Model 3

Cases/N

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

DKD

 

AIP (per unit)

709/2943

1.61(1.28,2.04)

< 0.001

1.75(1.35,2.26)

< 0.001

1.75(1.36,2.26)

< 0.001

Tertile 1 (< -0.05)

201/981

Reference

 

Reference

 

Reference

 

Tertile 2 (-0.05, 0.21)

248/981

1.31(1.09,1.57)

0.005

1.25(1.03,1.51)

0.024

1.27(1.05,1.54)

0.016

Tertile 3 (≥ 0.21)

260/981

1.43(1.19,1.73)

< 0.001

1.45(1.20,1.76)

< 0.001

1.47(1.21,1.79)

< 0.001

DR

 

AIP (per unit)

193/3360

0.90(0.57,1.42)

0.660

0.91(0.56,1.49)

0.717

0.92(0.57,1.49)

0.722

Tertile 1 (< -0.02)

66/1120

Reference

 

Reference

 

Reference

 

Tertile 2 (-0.02, 0.23)

64/1120

1.00(0.71,1.41)

0.998

1.04(0.73,1.48)

0.840

1.05(0.74,1.51)

0.774

Tertile 3 (≥ 0.23)

63/1120

1.00(0.71,1.41)

0.995

1.04(0.72,1.50)

0.845

1.05(0.72,1.52)

0.810

  1. Model 1: Crude model; Model 2: Adjusted for age, sex, HbA1c, duration of diabetes, BMI, SBP, ideal smoking, drinking; Model 3: Adjusted for covariables in model 2 plus LDL-C. DR refers to referable DR. Abbreviations: HR Hazard ratio, CI Confidence interval, AIP atherogenic index of plasma, DKD diabetic kidney disease, DR diabetic retinopathy
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Lipids in Health and Disease

ISSN: 1476-511X