Lipids in Health and Disease

Table 3 Univariate and multivariate linear regression analyses of clinical variables and indices in predicting nonfatal and fatal stroke

From: Residual risk of cardiovascular complications in statin-using patients with type 2 diabetes: the Taiwan Diabetes Registry Study

	Nonfatal stroke						Fatal Stroke
	Univariate			Multivariate (R square = 0.140)			Univariate			Multivariate (R square = 0.153)
	β	(95% Cl)	p value	β	(95% Cl)	p value	β	(95% Cl)	p value	β	(95% Cl)	p value
BMI	-0.002	(-0.001, -0.003)	0.001	-0.002	(-0.001, -0.003)	0.011	-0.00028	(-0.00012, -0.0004)	0.008	-0.0003	(-0.0001, -0.0004)	0.018
Waist	0.00004	(0.00034, -0.00026)	0.872				0.000021	(0.00007, -0.00003	0.658
DBP	-0.001	(-0.0007, -0.0013)	0.008	-0.001	(-0.0007, -0.0013)	0.041	0.0000003	(0.00005, -0.00005)	0.995
Complications
CKD	0.063	(0.072, 0.054)	< 0.001	0.053	(0.062, 0.044)	< 0.001	0.012	(0.014, 0.01)	< 0.001	0.01	(0.012, 0.008)	< 0.001
Retinopathy	0.019	(0.03, 0.008)	0.081				0.005	(0.007, 0.003)	0.019	0.002	(0.0035, -0.001)	0.332
Neuropathy	0.061	(0.082, 0.04)	0.004	0.046	(0.066, 0.026)	0.033	0.011	(0.015, 0.007)	0.002	0.008	(0.011, 0.005)	0.021
Medications
ACEI	0.024	(0.044, 0.004)	0.229				-0.001	(0.002, -0.004)	0.747
Diuretics	0.035	(0.047, 0.023)	0.004	0.013	(0.026, -0.0006)	0.340	0.006	(0.008, 0.004)	0.004	0.001	(0.003, -0.001)	0.567
CCB	0.046	(0.054, 0.038)	< 0.001	0.033	(0.042, 0.024)	< 0.001	0.009	(0.01, 0.008)	< 0.001	0.006	(0.008, 0.004)	< 0.001
ARB	0.027	(0.034, 0.02)	< 0.001	0.005	(0.014, -0.004)	0.085	0.006	(0.007, 0.005)	< 0.001	0.002	(0.003, 0.001)	0.288
Alpha	0.057	(0.09, 0.024)	0.085				0.009	(0.015, 0.003)	0.133
Insulin	0.009	(0.017, 0.001)	0.279				0.00147	(0.00296, -0.00002)	0.344
OAD	0.00002	(0.015, -0.015)	0.999				-0.00296	(-0.00036, -0.00556)	0.911
Laboratory data
LogTG	0.008	(0.020, -0.004)	0.491				0.001	(0.003, -0.001)	0.677
LDLc	-0.00025	(-0.00017, -0.00033)	0.001	-0.0002	(-0.0001, -0.0003)	0.038	-0.00003	(-0.00002, -0.00004)	0.017	-0.00002	(-0.00001, -0.00003)	0.068
LogALT	-0.041	(-0.029, -0.053)	0.001	-0.022	(-0.009, -0.033)	0.073	-0.008	(-0.006, -0.010)	< 0.001	-0.005	(-0.003, -0.007)	0.010
Fasting glucose	0.00064	(0.00069, 0.00059)	0.169				0.000003	(0.000011, -0.000005)	0.715

BMI, body mass index; DBP, diastolic blood pressure; CKD, chronic kidney disease; ACEi; angiotensin converting enzyme inhibitors; CCB, calcium channel blocker; ARB, angiotensin receptor blocker; OAD, oral antidiabetic drug; TG, triglyceride; LDL, low-density lipoprotein cholesterol; ALT; alanine transaminase

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