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Table 2 Univariate and multivariate linear regression analyses of clinical variables and indices in predicting nonfatal and fatal coronary heart disease

From: Residual risk of cardiovascular complications in statin-using patients with type 2 diabetes: the Taiwan Diabetes Registry Study

 

Nonfatal CHD

Fatal CHD

 

Univariate

Multivariate (R square = 0.281)

Univariate

Multivariate (R square = 0.238)

 

β

(95% Cl)

p value

β

(95% Cl)

p value

β

(95% Cl)

p value

β

(95% Cl)

p value

BMI

-0.003

(-0.002, -0.004)

0.008

-0.003

(-0.002, -0.004)

0.002

-0.0025

(-0.0018, -0.0034)

0.003

-0.002

(-0.001, -0.003)

0.004

Waist

0.0004

(0.0014, -0.0006)

0.413

   

0.00005

(0.0004, -0.0003)

0.897

   

DBP

0.001

(0.0014, 0.0004)

0.071

   

0.0051

(0.0055, 0.0047)

0.187

   

Complications

CKD

0.095

(0.112, 0.078)

< 0.001

0.080

(0.096, 0.064)

< 0.001

0.086

(0.099, 0.073)

< 0.001

0.073

(0.085, 0.061)

< 0.001

Retinopathy

0.001

(0.021, -0.019)

0.957

   

0.016

(0.031, 0.001)

0.300

   

Neuropathy

0.091

(0.130, 0.052)

0.019

0.074

(0.107, 0.041)

0.028

0.07

(0.099, 0.041)

0.017

0.054

(0.080, 0.028)

0.037

Medications

ACEI

-0.014

(0.023, -0.051)

0.713

   

-0.002

(0.026, -0.03)

0.931

   

Diuretics

0.014

(0.037, -0.009)

0.547

   

0.021

(0.038, 0.004)

0.222

   

CCB

0.035

(0.051, 0.019)

0.029

0.031

(0.045, 0.017)

0.027

0.039

(0.051, 0.027)

0.001

0.035

(0.046, 0.024)

0.001

ARB

0.012

(0.026, -0.002)

0.402

   

0.02

(0.03, 0.01)

0.061

   

Alpha

0.076

(0.137, 0.015)

0.213

   

0.075

(0.121, 0.029)

0.105

   

Insulin

0.055

(0.071, 0.039)

< 0.001

0.035

(0.045, 0.017)

0.011

0.051

(0.063, 0.039)

< 0.001

0.033

(0.044, 0.022)

0.002

OAD

-0.043

(-0.015, -0.071)

0.122

   

-0.029

(-0.008, -0.05)

0.162

   

Laboratory data

LogTG

0.189

(0.209, 0.169)

< 0.001

0.149

(0.179, 0.139)

< 0.001

0.093

(0.109, 0.077)

< 0.001

0.064

(0.080, 0.048)

< 0.001

LDLc

0.001

(0.0011, 0.0009)

< 0.001

0.001

(0.00113, 0.0009)

< 0.001

0.00046

(0.00057, 0.00035)

< 0.001

0.00311

(0.0032, 0.0030)

< 0.001

LogALT

-0.048

(-0.026, -0.070)

0.026

-0.047

(-0.027, -0.065)

0.018

-0.053

(-0.037, -0.069)

0.001

-0.042

(-0.027, -0.057)

0.005

Fasting glucose

0.001

(0.00108, 0.00092)

< 0.001

0.001

(0.0011, 0.0009)

< 0.001

0.0005

(0.00058, 0.00046)

< 0.001

0.0004

(0.0005, 0.0003)

< 0.001