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Table 3 Evaluation of predictive models for MACCE and all-cause mortality

From: Combination of the glycated hemoglobin levels and prognostic nutritional index as a prognostic marker in patients with acute coronary syndrome and type 2 diabetes mellitus

Ā 

C-index (95%CI)

P

NRI (95%CI)

P

IDI (95%CI)

P

All participants

MACCE

Established factors

0.664(0.598ā€“0.731)

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.681(0.614ā€“0.748)

0.24

0.266(0.035ā€“0.497)

0.023

0.005(0ā€“0.010)

0.023

All-cause mortality

Established factors

0.727 0.638ā€“0.817)

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.763(0.676ā€“0.849)

0.176

0.527(0.216ā€“0.838)

<ā€‰0.001

0.007(0.001ā€“0.013)

0.014

L-HbA1c group

MACCE

Established factors

0.726(0.633ā€“0.819)

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.724(0.626ā€“0.822)

0.917

0.183(āˆ’0.184 to 0.550)

0.327

0.003(āˆ’0.001 to 0.008)

0.133

All-cause mortality

Established factors

0.725(0.591ā€“0.858)

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.743(0.605ā€“0.881)

0.72

0.404(āˆ’0.095 to 0.903)

0.112

0.008(āˆ’0.002 to 0.018)

0.124

H-HbA1c group

MACCE

Established factors

0.686(0.604ā€“0.768)

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.694(0.610ā€“0.778)

0.665

0.331(0.037ā€“0.626)

0.027

0.009(0ā€“0.019)

0.034

All-cause mortality

Established factors

0.765(0.677ā€“0.854 )

Reference

/

Reference

/

Reference

Established factorsā€‰+ā€‰PNI

0.796(0.714ā€“0.879)

0.257

0.534(0.126ā€“0.942)

0.01

0.011(0ā€“0.023)

0.053

  1. Established risk factors included Age, Sex, BMI, Current smoker, Hypertension, Hyperlipidemia, Prior MI, HF, CKD, ACS type, TG, TC, LDL-C, and HbA1c. 95% CI, 95% confidence interval; IDI, integrated discrimination improvement; NRI, net reclassification improvement; PNI, prognostic nutritional index