Lipoprotein-associated phospholipase A2 predicts cardiovascular death in patients on maintenance hemodialysis: a 7-year prospective cohort study

Table 6 Interaction analyses of Lp-PLA2 with Lipids measures in relation to CV death and MACE occurrence

CV death	P for interaction (unadjusted)	P for interaction (adjusted)
Lp-PLA₂(as a dichotomous variable)
LDL-c	0.967	0.728
HDL-c	0.638	0.631
apoB	0.635	0.965
apoA	0.803	0.336
TG	0.973	0.875
Lp-PLA₂(as a continuous variable)(per 100U/L)
LDL-c	0.721	0.4
HDL-c	0.937	0.708
apoB	0.379	0.12
apoA	0.822	0.671
TG	0.939	0.993
MACEs	P for interaction (unadjusted)	P for interaction (adjusted)
Lp-PLA₂ (as a dichotomous variable)
LDL-c	0.884	0.875
HDL-c	0.634	0.948
apoB	0.681	0.928
apoA	0.615	0.665
TG	0.92	0.924
Lp-PLA₂(as a continuous variable)(per 100U/L)
LDL-c	0.909	0.98
HDL-c	0.74	0.749
apoB	0.394	0.189
apoA	0.824	0.845
TG	0.869	0.609

Covariates adjusted for CV death: age, dialysis vintage, vascular access, BMI, history of diabetes, coronary artery disease, albumin, hsCRP, creatine, uric acid, hs-cTNT, NT-proBNP. Covariates adjusted for MACE: age, dialysis vintage, vascular access, history of diabetes, coronary artery disease, history of taking ACEI, albumin, prealbumin, hs-CRP, creatine, uric acid, hs-cTNT, NT-proBNP

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