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Table 2 Patients characteristics in each response group (PR, SD, and PD)

From: Lipid alterations play a role in the integration of PD-1/PD-L1 inhibitors and anlotinib for the treatment of advanced non–small-cell lung cancer

Efficacy evaluation

PR

SD

PD

No of total patients

6

17

7

Gender

Male

4(66.67%)

16(94.12%)

5(71.43%)

Female

2(33.33%)

1(5.88%)

2(28.57%)

Age(years)

P = 0.8784 (PR vs. SD)

P = 0.7409 (PR vs. PD)

P = 0.3373 (SD vs. PD)

59.50 ± 9.73

62.17 ± 10.18

54.71 ± 13.91

Height(cm)

P = 0.1646 (PR vs. SD)

P = 0.8785 (PR vs. PD)

P = 0.1646 (SD vs. PD)

161.33 ± 9.11

165.47 ± 5.18

161.86 ± 5.15

Weight(Kg)

P = 0.8951 (PR vs. SD)

P = 0.5347 (PR vs. PD)

P = 0.8651 (SD vs. PD)

60.50 ± 15.24

59.76 ± 11.93

56.43 ± 5.99

BMI(Kg/m2)

P = 0.4892 (PR vs. SD)

P = 0.5287 (PR vs. PD)

P = 0.9610 (SD vs. PD)

22.97 ± 5.15

21.70 ± 3.65

21.61 ± 2.81

Smoking History

Non-smoker

2(33.33%)

2(11.76%)

1(14.29%)

Former smoker

4(66.67%)

15(88.24%)

6(85.71%)

ECOG performance status

0

3(50.00%)

5(29.41%)

2(28.57%)

1

3(50.00%)

12(70.59%)

5(71.43%)

Histology

Squamous cell carcinoma

3(50.00%)

7(41.18%)

5(71.43%)

Adenocarcinoma

3(50.00%)

10(58.82%)

2(28.57%)

Stage

IIIb-IIIc

3(50.00%)

2(11.76%)

0(0.00%)

IV

3(50.00%)

15(88.24%)

7(100.00%)

Metastatic

Liver

2(33.33%)

2(11.76%)

1(14.29%)

Brain

1(16.67%)

2(11.76%)

1(14.29%)

Bone

2(33.33%)

5(29.41%)

3(42.86%)

Lung

2(33.33%)

10(58.82%)

4(57.14%)

Pleural metastasis

0(0.00%)

3(17.65%)

1(14.29%)

PD-L1 status test

Data unavailable

3(50.00%)

3(17.65%)

3(42.86%)

0%

1(16.67%)

2(11.76%)

2(28.57%)

1–49%

1(16.67%)

3(17.65%)

2(28.57%)

≥ 50%

1(16.66%)

9(52.94%)

0(0.00%)