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Fig. 9 | Lipids in Health and Disease

Fig. 9

From: High-fat stimulation induces atrial neural remodeling by reducing NO production via the CRIF1/eNOS/P21 axi

Fig. 9

HFD induced atrial neural remodeling and increased the induction rate of AF, and TMZ improved neural remodeling and decreased the induction rate of AF. (A) Body weight trends of rats in the CON, HFD, and HFD + TMZ groups. (B) Blood biochemical indexes of rats in the CON, HFD, and HFD + TMZ groups. (C) MDA levels of rats in the CON, HFD, HFD + TMZ groups. (D) NO levels of rats in the CON, HFD, HFD + TMZ groups. (E, F) Cardiac electrophysiological indexes of the hearts of rats in the CON, HFD, and HFD + TMZ groups. (G) WB was used to detect the protein expression of PGP9.5, TH, CHAT, and eNOS in rats in the CON, HFD, and HFD + TMZ groups. (H) Immunohistochemistry of PGP9.5, TH, and CHAT in rats of the CON, HFD, and HFD + TMZ groups (20X). Scale bar = 100 μm

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