Table 3 Relationship between RC and the incident stroke in different models

RC

1.192 (1.108, 1.282) < 0.00001

1.097 (1.014, 1.188) 0.02200

1.087 (1.001, 1.180) 0.04675

RC (quartile)

 Q1

ref

ref

ref

 Q2

1.159 (0.976, 1.377) 0.09240

1.142 (0.961, 1.357) 0.13243

1.137 (0.957, 1.352) 0.14386

 Q3

1.219 (1.028, 1.444) 0.02244

1.134 (0.956, 1.346) 0.14907

1.130 (0.952, 1.341) 0.16290

 Q4

1.520 (1.292, 1.788) < 0.00001

1.277 (1.080, 1.510) 0.00431

1.261 (1.063, 1.495) 0.00777

Gender

 Male

ref

ref

 Female

1.162 (0.989, 1.365) 0.06746

1.193 (1.005, 1.415) 0.04370

 Age (years)

1.021 (1.015, 1.028) < 0.00001

1.020 (1.013, 1.027) < 0.00001

 BMI (kg/m²)

1.022 (1.008, 1.036) 0.00240

1.019 (1.005, 1.034) 0.00935

Drinking status

 Never drinkers

ref

ref

 Ever drinkers

0.891 (0.751, 1.057) 0.18545

0.893 (0.753, 1.060) 0.19543

 Current drinkers

0.870 (0.719, 1.052) 0.15021

0.876 (0.724, 1.060) 0.17200

Smoking status

 Never smokers

ref

ref

 Ever smokers

1.224 (0.991, 1.512) 0.06115

1.217 (0.984, 1.505) 0.06965

 Current smokers

1.240 (1.050, 1.464) 0.01106

1.236 (1.047, 1.460) 0.01246

Physical activity

 No

ref

ref

 Yes

0.901 (0.800, 1.014) 0.08424

0.906 (0.805, 1.021) 0.10586

Heart diseases

 No

ref

ref

 Yes

4.059 (3.580, 4.603) < 0.00001

3.967 (3.494, 4.504) < 0.00001

Hypertension

 No

ref

ref

 Yes

1.641 (1.445, 1.864) < 0.00001

1.605 (1.412, 1.826) < 0.00001

Diabetes mellitus

 No

ref

ref

 Yes

1.418 (1.176, 1.710) 0.00025

1.363 (1.127, 1.647) 0.00137

Lipid therapy

 No

ref

 Yes

1.281 (1.059, 1.550) 0.01077

 CRP (mg/L)

1.006 (1.000, 1.013) 0.05031

 Scr (mg/dL)

1.109 (0.801, 1.535) 0.53333

 Cystatin C (mg/L)

1.035 (0.786, 1.363) 0.80615