Effects of canola or olive oil on plasma lipids, lipoprotein-associated phospholipase A2 and inflammatory cytokines in patients referred for coronary angiography

Table 5 Measures of biochemical variables by intervention groups ^a

Variable	Olive Oil group (n = 22)			Canola Oil group (n = 20)			P ^c
Variable	Baseline	6-Week	Δ value ^b	Baseline	6-Week	Δ value ^b	P ^c
TC (mg/dL)	116.77 ± 25.15	124.36 ± 28.94	8.45 ± 17.67	136.25 ± 46.45	133.35 ± 47.54	−2.90 ± 16.81	0.10
LDL-C (mg/dL)	63.64 ± 13.72	67.36 ± 17.39	3.68 ± 11.27	74.65 ± 30.46	72.90 ± 28.98	−1.75 ± 9.03	0.16
sd-LDL (mg/dL)	24.14 ± 10.32	23.14 ± 11.18	−0.91 ± 6.34	22.10 ± 7.51	21.00 ± 9.48	− 1.10 ± 6.35	0.62
HDL-C (mg/dL)	37.73 ± 7.92	39.50 ± 7.46	1.50 ± 5.80	42.90 ± 6.49	43.15 ± 8.33	0.35 ± 5.21	0.79
TC/HDL-C	3.17 ± 0.47	3.25 ± 0.71	0.08 ± 0.39	3.06 ± 0.72	3.10 ± 0.83	0.03 ± 0.33	0.81
TG (mg/dL)	112.73 ± 33.04	120.50 ± 61.38	7.63 ± 36.45	122.45 ± 31.94	126.05 ± 35.40	3.90 ± 20.92	0.32
Lp-PLA₂ mass (ng/mL)	5.66 ± 4.09	6.00 ± 4.51	0.34 ± 1.57	3.96 ± 2.45	2.99 ± 1.65	− 0.97 ± 1.84 ^†	0.008
Lp-PLA₂ Activity (nmol/min/mL)	0.022 ± 0.013	0.021 ± 0.017	− 0.000 ± 0.008	0.012 ± 0.003	0.010 ± 0.004	− 0.001 ± 0.002	0.74
IL-6 (pg/mL)	21.95 ± 20.38	12.49 ± 13.70	− 9.46 ± 9.46 ^†	19.53 ± 10.52	18.62 ± 8.55	−0.90 ± 6.80	0.008
C3 (g/L)	199.32 ± 35.04	200.68 ± 33.63	1.36 ± 36.64	205.30 ± 44.46	223.50 ± 42.40	18.10 ± 49.00	0.08
C4 (g/L)	38.82 ± 11.99	36.23 ± 9.48	−2.59 ± 9.09	39.20 ± 9.03	34.60 ± 10.35	−4.55 ± 12.43	0.52
C3/C4	5.56 ± 1.98	5.37 ± 2.08	0.23 ± 0.91	5.37 ± 2.08	6.36 ± 2.45	0.99 ± 2.53	0.27

^a All values are Mean ± SD
^b Change of parameter between 6-week and baseline (6-week minus baseline)
^c The values for 6-week were analyzed using ANCOVA with baseline values as covariate
^† Significantly different from baseline. Data were compared using Paired t-test
TC Total Cholesterol, LDL-C Low Density Lipoprotein-Cholesterol, sd-LDL Small Dense LDL, HDL High Density Lipoprotein-Cholesterol, TG Triglyceride, Lp-PLA₂ Lipoprotein-Associated Phospholipase A₂, IL-6 Interleukin-6, C3 Complement component 3, C4 Complement component 4

ISSN: 1476-511X