From: Contribution of CYP24A1 variants in coronary heart disease among the Chinese population
SNP | Genotype | Location | Cases | Controls | MAF-Case | MAF-Control | HWE P | OR(95%CI) | P | HaploReg |
---|---|---|---|---|---|---|---|---|---|---|
rs2762934 | A/G | 3′-UTR | 116/890 | 108/908 | 0.115 | 0.106 | 1.000 | 1.10 (0.83–1.45) | 0.519 | Enhancer histone marks, DNAse, Motifs, Proteins bound, Motifs changed |
rs1570669 | A/G | Intronic | 379/629 | 401/615 | 0.376 | 0.395 | 0.403 | 0.92 (0.77–1.11) | 0.388 | DNAse, Proteins bound, Motifs changed, NHGRI/EBI GWAS hits |
rs6068816 | T/C | Synonymous | 380/622 | 330/680 | 0.379 | 0.327 | 0.920 | 1.26 (1.05–1.51) | 0.014 | SiPhy cons, DNAse, Proteins bound, Motifs changed, |
rs2296241 | A/G | Synonymous | 423/587 | 469/547 | 0.419 | 0.462 | 0.212 | 0.84 (0.71–1.00) | 0.052 | SiPhy cons, Enhancer histone marks, DNAse, Proteins bound, Motifs changed, Selected eQTL hits |