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Table 6 Statin persistence over time in patient subgroup with ASCVD

From: Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims analysis

Cohort

 

Time (Years)

0.5

1

2

3

4

5

A) Elevated-TG analysis

Study population with baseline ASCVD (1)

Proportion

0.6200

0.4829

0.3537

0.2805

0.2372

0.2028

At risk

4247

2830

1623

1053

640

439

Study population with no baseline ASCVD (2)

Proportion

0.5986

0.4661

0.3325

0.2628

0.2140

0.1819

At risk

9712

6442

3640

2395

1394

932

Comparison group with baseline ASCVD (3)

Proportion

0.6171

0.4884

0.3560

0.2856

0.2350

0.2023

At risk

4157

2830

1623

1098

626

427

Comparison group with no baseline ASCVD (4)

Proportion

0.5902

0.4655

0.3392

0.2707

0.2232

0.1900

At risk

9639

6566

3791

2539

1492

1008

Clustered P values for between-group comparisons in the elevated-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.001

0.801

0.005

<0.001

0.520

0.002

B) High-TG analysis

Study population with baseline ASCVD (1)

Proportion

0.6193

0.4722

0.3411

0.2691

0.2228

0.1949

At risk

1952

1247

710

464

277

198

Study population with no baseline ASCVD (2)

Proportion

0.5795

0.4500

0.3166

0.2485

0.1970

0.1653

At risk

4513

2994

1661

1081

622

407

Comparison group with baseline ASCVD (3)

Proportion

0.6033

0.4778

0.3507

0.2754

0.2279

0.1932

At risk

1877

1271

724

476

263

174

Comparison group with no baseline ASCVD (4)

Proportion

0.5809

0.4524

0.3260

0.2640

0.2214

0.1922

At risk

4551

3057

1750

1181

710

476

Clustered P values for between-group comparisons in the high-TG analysis

  

1 vs 2

1 vs 3

1 vs 4

2 vs 3

2 vs 4

3 vs 4

  

0.001

0.943

0.066

0.001

0.063

0.058

  1. Kaplan-Meier analysis. Clustered P values were calculated using Cox proportional hazard model with cohort as independent variable. Study population is the elevated-TG cohort (TG ≥150 mg/dL) and high-TG subcohort and their propensity score matched comparators with TG < 150 mg/dL and HDL-C > 40 mg/dL
  2. ASCVD atherosclerotic cardiovascular disease, HDL-C high-density lipoprotein cholesterol, TG triglycerides
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Lipids in Health and Disease

ISSN: 1476-511X