Non-HDL-cholesterol to HDL-cholesterol ratio is an independent risk factor for liver function tests abnormalities in geriatric population

Table 3 Odds ratios (95% confidence intervals) for incident LFTs abnormalities by Non-HDL/HDL levels tertiles

	Unadjusted Odds ratio (95% CI)	P Value	Model 1^a Odds ratio (95% CI)	P Value	Model 2^b Odds ratio (95% CI)	P Value
ALT + AST
NonHDLc/HDLc	1.36 (1.06, 1.73)	0.015	1.65 (1.08, 2.52)	0.020	1.67 (1.08, 2.56)	0.020
Tertiles NonHDLc/HDLc
Tertile 1	1		1		1
Tertile 2	1.37 (0.81, 2.30)	0.238	1.80 (0.91, 3.56)	0.091	1.80 (0.90, 3.58)	0.095
Tertile 3	1.84 (1.12, 3.01)	0.016	2.80 (1.17, 6.70)	0.021	2.85 (1.18, 6.93)	0.020
ALT
NonHDLc/HDLc	1.35 (1.04, 1.74)	0.022	1.66 (1.07, 2.57)	0.024	1.70 (1.08, 2.66)	0.021
Tertiles NonHDLc/HDLc
Tertile 1	1		1		1
Tertile 2	1.35 (0.79, 2.33)	0.275	1.80 (0.89, 3.64)	0.105	1.83 (0.89, 3.78)	0.100
Tertile 3	1.81 (1.08, 3.03)	0.024	2.82 (1.14, 7.00)	0.025	2.96 (1.17, 7.48)	0.022
AST
NonHDLc/HDLc	1.29 (0.93,1.80)	0.135	1.52 (0.85, 2.71)	0.161	1.48 (0.83, 2.63)	0.184
Tertiles NonHDLc/HDLc
Tertile 1	1		1		1
Tertile 2	1.37 (0.68, 2.76)	0.379	1.72 (0.69, 4.31)	0.247	1.62 (0.65, 4.04)	0.300
Tertile 3	1.67 (0.85, 3.28)	0.135	2.40 (0.72, 8.00)	0.154	2.25 (0.69, 7.38)	0.180

HDLc high-density lipoprotein cholesterol
^a Model 1 adjusted for age, gender, body mass index, systolic BP, diastolic BP, triglycerides, total cholesterol,
LDL- cholesterol, HDL-cholesterol, Non-HDL-cholesterol, fasting plasma glucose
^b Model 2 adjusted for model 1 plus serum creatinine, blood urea nitrogen, alanine transaminase, aspartate, transaminase, total bilirubin, history of hypertension, history of diabetes mellitus

ISSN: 1476-511X