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Table 5 Effect size of AST/ALT on baPWV in prespecified and exploratory subgroups

From: AST to ALT ratio and arterial stiffness in non-fatty liver Japanese population:a secondary analysis based on a cross-sectional study

Characteristic

No of participants

Effect size(95%CI)

P for interaction

Age (year)

  

0.001

  ≤ 60

98

15.6 (6.3, 25.0)

 

  > 60

531

−0.8 (−5.7, 4.1)

 

Sex

  

0.32

 male

372

5.5 (−0.5, 11.5)

 

 female

274

1.3 (−4.9, 7.6)

 

5.4 (−2.7, 13.5)*

Current smoking

  

0.83

 no

517

3.0 (−1.6, 7.5)

 

 yes

129

1.5 (−11.1, 14.2)

 

Ex-Smoking

  

0.88

 no

346

2.6 (−3.2, 8.4)

 

 yes

300

3.2 (−3.1, 9.5)

 

Regular Exercise (> 1 week)

  

0.08

 no

488

0.2 (−4.6, 5.1)

 

 yes

146

8.8 (0.1, 17.5)

 

Alcohol consumption

  

0.54

  ≤ 40 (g/week)

419

1.1 (−4.1, 6.3)

 

 40–140

107

8.1 (−2.8, 18.9)

 

 140–280

57

6.3 (−14.7, 27.4)

 

  > 280

58

8.8 (−8.0, 25.7)

 

BMI

  

0.54

  < 18.5

36

11.7 (−10.8, 34.1)

 

  > =18.5, < 23

386

5.8 (0.4, 11.2)

 

  > =23

224

1.6 (−6.2, 9.5)

 

Hypertension

  

0.90

 no

585

3.3 (−1.4, 7.9)

 

 yes

61

2.2 (−14.3, 18.7)

 

Uric acid (tertile)

  

032

 low

298

3.9 (−3.7, 11.5)

 

 middle

308

−3.8 (−12.9, 5.2)

 

 high

306

4.5 (−5.4, 14.4)

 
  1. Note 1:Above model adjusted for sex; age; BMI; SBP; DBP; γ-GTP; fasting glucose; uric acid; TC; TG; HDL-C; LDL; smoking status (current and ex-); excise; e-GFR; ABIM; alcoholic consumption
  2. Note 2:In each case, the model is not adjusted for the stratification variable
  3. Note 3: * adjusted menopausal status + sex; age; BMI; SBP; DBP; γ-GTP; fasting glucose; uric acid; TC; TG; HDL-C; LDL; smoking status (current and ex-); excise; e-GFR; ABIM; alcoholic consumption