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Table 1 Antidiabetic effects of DKE

From: Hypolipidemic activity of Dracocephalum kotschyi involves FOXO1 mediated modulation of PPARγ expression in adipocytes

Groups

days

Glucose (mg/dl)

TG (mg/dl)

TC (mg/dl)

LDL (mg/dl)

HDL (mg/dl)

Normal control

0

131.25 ± 3.85*

61.73 ± 2.05*

66.45 ± 5.85*

18.01 ± 1.23*

34.02 ± 0.86*

14

132.00 ± 2.20*

63.98 ± 3.52*

66.81 ± 3.44*

19.55 ± 1.78*

32.68 ± 1.44*

28

127.00 ± 5.30*

62.33 ± 3.87*

67.88 ± 5.31*

20.41 ± 1.26*

35.04 ± 1.46*

Diabetic control

0

290.80 ± 18.20

120.44 ± 4.58

107.76 ± 5.67

56.72 ± 4.05

23.38 ± 0.77

14

342.36 ± 3.96

127.36 ± 4.69

116.54 ± 6.04

65.22 ± 4.11

22.46 ± 1.61

28

393.87 ± 7.97

143.36 ± 8.07

117.09 ± 1.46

76.90 ± 4.24

21.18 ± 1.82

DKE (0.25 ml/rat)

0

412.58 ± 17.82

110.35 ± 8.69

101.72 ± 6.22

66.11 ± 3.56

20.16 ± 1.30

14

384.43 ± 11.07

93.33 ± 4.99*

99.53 ± 5.85

52.80 ± 1.56

23.57 ± 0.57

28

321.07 ± 4.00*

74.15 ± 3.33*

80.74 ± 2.19*

43.75 ± 2.50*

24.34 ± 1.72

DKE (0.5 ml/rat)

0

379.43 ± 8.08

117.16 ± 8.22

106.77 ± 3.59

57.39 ± 1.85

22.16 ± 0.69

14

365.22 ± 3.825

77.62 ± 3.08*

97.88 ± 2.37

44.17 ± 2.06*

26.64 ± 0.77

28

284.80 ± 6.40*

66.33 ± 1.76*

69.89 ± 4.17*

35.26 ± 3.99*

30.74 ± 1.15*

Pioglitazone

0

342.73 ± 21.44

99.78 ± 4.70

116.91 ± 2.44

61.99 ± 3.57

23.23 ± 0.69

14

255.89 ± 7.73*

72.66 ± 3.40*

92.14 ± 1.97*

41.26 ± 1.00*

29.13 ± 0.92

28

178.67 ± 10.01*

63.63 ± 2.82*

72.38 ± 4.46*

24.51 ± 2.04*

33.25 ± 1.05*

  1. Each value represents the mean ± SD (n = 6). *P < 0.05 statistically different compared to the diabetic control by Student’s t-test