Table 3 Association of ACE2 SNPs with decreased HDL-C (< 1.0Â mmol/L) in study subjects
ACE2 SNPs | HDL-C (N/%) | OR(95%CI)a | P-valuea | ||
|---|---|---|---|---|---|
≥ 1.0 mmol/L | <  1.0 mmol/L | ||||
rs2106809 | CC + CT | 215 (42.1) | 81 (65.3) | 2.49 (1.58–3.91) | < 0.001 |
| Â | TT | 296 (57.9) | 43 (34.7) | 1.00 | Â |
rs2285666 | CC | 194 (38.0) | 37 (29.8) | 1.00 | Â |
|  | TT + CT | 317 (62.0) | 87 (70.2) | 1.73 (1.10–2.71) | 0.017 |
rs4646142 | CC + CG | 318 (62.2) | 85 (68.5) | 1.58 (1.01–2.46) | 0.044 |
| Â | GG | 193 (37.8) | 39 (31.5) | 1.00 | Â |
rs4646155 | CC | 453 (88.6) | 92 (74.2) | 1.00 | Â |
|  | TT + CT | 58 (11.4) | 32 (25.8) | 2.85 (1.71–4.75) | < 0.001 |
rs4646188 | CC | 123 (24.1) | 36 (29.0) | 1.00 | Â |
|  | TT + CT | 388 (75.9) | 88 (71.0) | 1.88 (1.05–3.35) | 0.033 |