Association of LIPC -250G/A and -514C/T polymorphisms and hypertension: a systematic review and meta-analysis

Table 1 The character of included literatures

Author	Public Year	Location	Detection method	SNP	NOS	Group	N	Age	Gender (Male/Female)	SNP			HWE
Author	Public Year	Location	Detection method	SNP	NOS	Group	N	Age	Gender (Male/Female)	CC(GG)	CT(GA)	TT(AA)	Χ²^a	P
Bernard N	2007	Canada	PCR-ASO	rs1800588	6	HDCP	106	27 ± 4	0/106	63	40	3	2.776	0.0957
Bernard N	2007	Canada	PCR-ASO	rs1800588	6	Control	169	27 ± 4	0/169	56	37	13	2.776	0.0957
Lin H	2014	China	PCR-RFLP	rs1800588	6	HDCP	321	29.1 ± 5.6	0/321	127	151	43	0.267	0.6055
				rs1800588		Control	331	27.9 ± 4.2	0/331	126	160	45	0.267	0.6055
				rs2070895		HDCP	321	29.1 ± 5.6	0/321	120	151	50	0.081	0.7754
				rs2070895		Control	331	27.9 ± 4.2	0/331	119	161	51	0.081	0.7754
Ríosgonzález BE	2014	Mexico	PCR-RFLP,PCR-AIRS	rs1800588	5	Case	160	47 ± 10	121/39	38	67	49	0.002	0.9691
Ríosgonzález BE	2014	Mexico	PCR-RFLP,PCR-AIRS	rs1800588	5	Control	160	47 ± 11	114/46	35	78	44	0.002	0.9691
Yin RX1	2012	China	PCR-RFLP	rs2070895	7	Case	330	49.9 ± 16.2	330/0	124	168	38	1.058	0.3036
Yin RX1	2012			rs2070895		Control	338	48.8 ± 11.8	338/0	158	152	28	1.058	0.3036
Yin RX2	2012			rs2070895		Case	340	48.3 ± 15.8	0/340	143	131	66	4.716	0.0299
Yin RX2	2012			rs2070895		Control	344	47.1 ± 11.2	0/344	162	160	22	4.716	0.0299

SNP Single Nucleotide Polymorphism, ^a: likelihood-ratio Χ²; NOS Newcastle-Ottawa Scale, N The total number of including, SNP Single nucleotide polymorphisms, HWE Hardy-Weinberg equilibrium tests of control, HDCP Hypertensive disorders complicating pregnancy, 1:Male; 2: Female; PCR-ASO Polymerase chain reaction-allele-specific oligonucleotide, PCR-RFLP Polymerase chain reaction-restriction fragment length polymorphism, PCR-AIRS Polymerase chain reaction-artificial introduction of restriction sites

ISSN: 1476-511X