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Table 2 The unadjusted association between baseline variables and NAFLD status at the end of follow-up (n = 2717)

From: Non-HDL-cholesterol to HDL-cholesterol ratio is a better predictor of new-onset non-alcoholic fatty liver disease than non-HDL-cholesterol: a cohort study

Variable

Statistics

Hazard ratio (95% CI)

P value

Age (yr)

40.64 ± 12.00

1.01 (1.00, 1.02)

0.049

Sex, n (%)

  

< 0.001

 Female

1329 (48.91)

1.0

 

 male

1388 (51.09)

2.70 (2.06, 3.54)

 

Body mass index (kg/m2)

22.28 ± 2.66

1.34 (1.29, 1.39)

< 0.001

Hypertension, n (%)

309 (12.02)

1.58 (1.15, 2.16)

0.004

Systolic BP (mmHg)

112.67 ± 14.27

1.02 (1.01, 1.03)

< 0.001

Diastolic BP (mmHg)

75.34 ± 9.22

1.04 (1.03, 1.06)

< 0.001

Fasting plasma glucose (mmol/l)

4.85 ± 0.48

1.40 (1.10, 1.78)

0.005

Triglycerides (mmol/l)

0.99 (0.48)

1.68 (1.54, 1.84)

< 0.001

Total cholesterol (mmol/l)

4.65 ± 0.78

1.49 (1.29, 1.72)

< 0.001

LDLc (mmol/l)

2.45 ± 0.65

1.76 (1.49, 2.08)

< 0.001

HDLc (mmol/l)

1.56 ± 0.35

0.15 (0.10, 0.22)

< 0.001

NonHDLc (mmol/l)

3.08 ± 0.77

1.96 (1.71, 2.24)

< 0.001

NonHDLc/HDLc

2.10 ± 0.77

2.19 (1.94, 2.47)

< 0.001

ALT (U/L)

20.44 ± 11.04

1.04 (1.04, 1.05)

< 0.001

AST (U/L)

21.09 ± 6.54

1.04 (1.03, 1.05)

< 0.001

  1. Data are expressed as the mean ± SD, median (interquartile range), or percentage
  2. BP Blood pressure; LDLc Low-density lipoprotein cholesterol; HDLc High-density lipoprotein cholesterol; ALT Alanine aminotransferase; AST Aspartate aminotransferase
  3. Hypertension was defined as blood pressure ≥ 140/90 mmHg or use of anti-hypertensive treatment