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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

Fig. 4

FGF21 attenuated the progress of atherosclerosis. a The level of serum FGF21 increased in the apoE−/− mice compared with C57BL6 mice as measured by ELISA. **p < 0.01 vs. C57BL6. b The expression of FGF21 in the aortic root region of the heart increased in apoE−/− mice compared with that in C57BL6 mice assessed by IHC analyses (n = 6). **p < 0.01 vs. C57BL6. c FGF21 reversed the smooth muscle arrangement disorder and thickening and the plaque formation in atherosclerosis of apoE−/− mouse hearts detected by HE staining (n = 6)

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