A study of ghrelin and leptin levels and their relationship to metabolic profiles in obese and lean Saudi women with polycystic ovary syndrome (PCOS)

Table 6 Correlation of homeostasis model assessment of insulin sensitivity (HOMA-S) and the clinical and metabolic profile of patients with polycystic ovary syndrome (POCS) and healthy controls

Correlation between HOMA-S and:	PCOS		Control
Correlation between HOMA-S and:	r	p	r	p
Age	−0.320	< 0.0001^**	0.074	0.420
Body mass index (BMI)	0.194	0.027^*	0.317	< 0.0001^**
Weight/height ratio	0.180	0.056	0.343	< 0.0001^**
Cholesterol	0.079	0.370	0.145	0.111
Triglyceride	0.185	0.035^*	0.153	0.095
HDL-C	−0.265	0.002^**	−0.118	0.199
LDL-C	0.175	0.047^*	0.168	0.065
Leptin	0.175	0.046^*	0.326	< 0.0001^**
Fasting ghrelin	−0.293	0.001^**	−0.257	0.004^**
Fasting insulin	0.832	< 0.0001^**	0.540	< 0.0001^**
Fasting glucose	−0.210	0.017^*	−0.415	< 0.0001^**
HOMA-IR (insulin resistance)	0.698	< 0.0001^**	0.405	< 0.0001^**

ISSN: 1476-511X