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Table 1 The characteristics of the included studies

From: The relationship between apolipoprotein genes polymorphisms and susceptibility to osteonecrosis of the femoral head: a meta-analysis

Author, Year, Location

Study Year

NOS

Age

Gender(Male)

SNPs

ONFH

Control

HWE

ONFH/Control

ONFH/Control

N

WH

HT

MH

N

WH

HT

MH

Χ2*

P

Yin JM, [32] 2014, China

2001.11–2013.9

7

44.6 ± 11.3/44.7 ± 11.7

326/278

ApoA1-G75A(rs1799837)

429

215

73

141

368

170

114

84

43.758

< 0.001

ApoB-EcoR I(rs1042031)

429

391

38

0

368

324

44

0

1.488

0.2226

ApoB-Xba I(rs693)

429

394

35

0

368

327

41

0

1.281

0.2578

ApoB-3′-VNTR

429

336

93

0

368

299

69

0

3.938

0.0583

Hirata T, [29] 2007, Japan

1983–2004

7

40.8(20–64)/ 36.1 (9–63)

22/91

ApoB-C7623T

33

27

6

0

122

115

6

1

2.755

0.0969

ApoB-G12619A

34

33

1

0

123

112

11

0

0.2690

0.6037

ApoA1-G75A(rs1799837)

33

22

11

120

86

34

–

–

Wang XY, [31] 2008, China

2003.10–2005.9

5

41.6 ± 10.3/40.7 ± 14.7

98/48

ApoA1-G75A(rs1799837)

143

70

20

53

92

45

28

19

10.447

0.0012

ApoB-EcoR I(rs1042031)

143

125

18

0

92

82

10

0

0.304

0.5815

ApoB-Xba I(rs693)

143

126

17

0

92

87

5

0

0.072

0.7888

ApoB-3′-VNTR

142

109

33

0

92

73

18

1

0.009

0.9247

Zeng P, [19] 2014, China

2010.1–2013.12

5

39.85 ± 10.07/41.04 ± 13.61

53/38

ApoB-EcoR I(rs1042031)

108

95

13

0

98

96

2

0

0.010

0.9187

ApoB-Xba I(rs693)

108

89

19

0

98

92

6

0

0.098

0.7546

Wei XD, [30] 2015, China

2011.1–2012.12

6

39 ± 10/41 ± 14

28/14

ApoA1-G75A(rs1799837)

45

32

13

0

30

28

2

0

0.036

0.8502

ApoB-Xba I(rs693)

45

41

4

0

30

26

4

0

0.153

0.6956

ApoB-EcoR I(rs1042031)

45

31

14

0

30

27

3

0

0.083

0.7731

Wei BF, [28] 2011, China

2007.1–2009.12

5

35.17 ± 11.73/34.76 ± 11.94

27/30

ApoB-C7623T

63

57

6

0

71

71

0

0

–

1.000

ApoB-G12619A

63

56

7

0

71

69

2

0

0.014

0.9042

  1. SNP Single Nucleotide Polymorphism, Χ2* likelihood-ratio Χ2, WH Wild homozygote, HT Heterozygote, MH mutational homozygote, NOS Newcastle-Ottawa Scale, N The total number of including, ONFH Osteonecrosis of the Femeral Head, HWE Hardy-Weinberg equilibrium tests