Plasma apolipoprotein E level is associated with the risk of endobronchial biopsy-induced bleeding in patients with lung cancer

Table 3 Multivariate Regression Analysis of ApoE With the Risk of Biopsy-induced Bleeding

ApoE (mg/dL)	Biopsy-induced bleeding OR (95% CI) P-value
ApoE (mg/dL)	Non-adjust	Adjust I^a	Adjust II^b
< 3.5	Ref.	Ref.	Ref.
3.6–5.9	0.59 (0.42, 0.84) 0.0029	0.63 (0.43, 0.91) 0.0140	0.64 (0.43, 0.94) 0.0228
≧ 6.0	0.74 (0.39, 1.39) 0.3487	0.86 (0.44, 1.71) 0.6731	0.85 (0.41, 1.76) 0.6634

^aAdjust I adjust for: HDLC, smoking, location of lesion, histological types, stage, and CRP
^bAdjust II adjust for: Sex, Age, SBP, DBP, smoking, TC, triglyceride, HDLC, LDLC, location of lesion, histological types, stage, diabetes, hypertension, COPD, CHD, ALT, AST, and CRP
Apo apolipoprotein, HDLC high density lipoprotein cholesterol, CRP C-reactive protein, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDLC low density lipoprotein cholesterol, COPD Chronic obstructive pulmonary disease, CHD coronary heart disease, ALT alanine aminotransferase, AST aspartate aminotransferase

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