Table 2 Univariate Analysis of Possible Influencing Factors of the Risk of Biopsy-induced Bleeding
Variables | Biopsy-induced Bleeding | |
|---|---|---|
OR (95% CI) | P value | |
Age (y), median (range) | 1.01 (0.99, 1.03) | 0.1909 |
Sex, n (%) | ||
Female | Ref. | |
Man | 1.41 (0.94, 2.13) | 0.0990 |
Smoking, n (%) | ||
Never | Ref. | |
Former | 1.83 (1.12, 2.97) | 0.0153 |
Current | 1.47 (1.02, 2.13) | 0.0411 |
SBP (mmHg) | 0.99 (0.99, 1.00) | 0.1595 |
DBP (mmHg) | 1.00 (0.99, 1.02) | 0.5100 |
Location of lesion, n (%) | ||
Peripheral bronchi | Ref. | |
Central airway | 3.50 (2.13, 5.72) | < 0.0001 |
Stage, n (%) | ||
Early | Ref. | |
Advanced | 1.88 (1.35, 2.63) | 0.0002 |
Histological types, n (%) | ||
Adenocarcinoma | Ref. | |
Squamous cell carcinoma | 2.77 (1.79, 4.26) | < 0.0001 |
SCLC | 2.21 (1.29, 3.78) | 0.0037 |
Others | 2.47 (1.11, 5.48) | 0.0260 |
COPD, n (%) | ||
No | Ref. | |
Yes | 1.08 (0.57, 2.06) | 0.8155 |
Hypertension, n (%) | ||
No | Ref. | |
Yes | 1.10 (0.76, 1.61) | 0.6085 |
Diabetes, n (%) | ||
No | Ref. | |
Yes | 0.82 (0.38, 1.78) | 0.6214 |
CHD, n (%) | ||
No | Ref. | |
Yes | 1.17 (0.47, 2.91) | 0.7356 |
Triglyceride (mmol/L) | 0.80 (0.61, 1.05) | 0.1084 |
TC (mmol/L) | 0.91 (0.77, 1.07) | 0.2707 |
HDLC (mmol/L) | 0.52 (0.31, 0.88) | 0.0146 |
LDLC (mmol/L) | 0.89 (0.71, 1.11) | 0.2856 |
Apo E (mg/dL) | 0.89 (0.80, 1.00) | 0.0488 |
Apo B (g/L) | 0.76 (0.46, 1.27) | 0.2949 |
Homocysteine (μmol/L) | 1.00 (0.99, 1.01) | 0.4514 |
WBC (×109/L) | 1.03 (0.98, 1.08) | 0.2423 |
Neutrophils (×109/L) | 1.04 (0.99, 1.10) | 0.0856 |
Hemoglobin (g/L) | 1.00 (0.99, 1.00) | 0.7850 |
platelets (× 109/L) | 1.00 (1.00, 1.00) | 0.1130 |
CRP (mg/L) | 1.01 (1.00, 1.01) | 0.0093 |
PT (S) | 0.99 (0.98, 1.01) | 0.2445 |
APTT (S) | 0.99 (0.98, 1.00) | 0.1430 |
ALT (IU/L) | 1.00 (0.99, 1.01) | 0.6193 |
AST (IU/L) | 1.00 (0.99, 1.01) | 0.9870 |