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Table 1 Baseline Characteristics and Blood tests of the Study Participants

From: Plasma apolipoprotein E level is associated with the risk of endobronchial biopsy-induced bleeding in patients with lung cancer

Characteristics

Biopsy-induced bleeding

No (n = 391)

Yes (n = 224)

Age (y), median (range)

65.00 (32–85)

65.50 (36–82)

Sex, n (%)

 Female

94 (24.04)

41 (18.30)

 Man

297 (75.96)

183 (81.70)

Smoking, n (%)

 Never

158 (40.41)

68 (30.36)

 Former

56 (14.32)

44 (19.64)

 Current

177 (45.27)

112 (50.00)

SBP (mmHg)

132.34 ± 0.98

130.01 ± 1.37

DBP (mmHg)

77.95 ± 0.58

78.60 ± 0.82

Location of lesion, n (%)

 Peripheral bronchi

362 (92.58)

175 (78.12)

 Central airway

29 (7.42)

49 (21.88)

Stage, n (%)

 Early

237 (60.61)

98 (44.95)

 Advanced

154 (39.39)

120 (55.05)

Histological types, n (%)

 Adenocarcinoma

130 (33.25)

36 (16.07)

 Squamous cell carcinoma

175 (44.76)

134 (59.82)

 SCLC

67 (17.14)

41 (18.30)

 Others

19 (4.86)

13 (5.80)

COPD, n (%)

 No

365 (93.35)

208 (92.86)

 Yes

26 (6.65)

16 (7.14)

Hypertension, n (%)

 No

297 (75.96)

166 (74.11)

 Yes

94 (24.04)

58 (25.89)

Diabetes, n (%)

 No

370 (94.63)

214 (95.54)

 Yes

21 (5.37)

10 (4.46)

CHD, n (%)

 No

379 (96.93)

216 (96.43)

 Yes

12 (3.07)

8 (3.57)

Triglyceride (mmol/L)

1.24 ± 0.03

1.15 ± 0.05

TC (mmol/L)

4.19 ± 0.06

4.10 ± 0.06

HDLC (mmol/L)

1.18 ± 0.02

1.12 ± 0.02

LDLC (mmol/L)

2.84 ± 0.04

2.77 ± 0.05

Apo E (mg/dL)

3.90 ± 0.07

3.65 ± 0.10

Apo B (g/L)

1.02 ± 0.02

0.99 ± 0.02

Homocysteine (μmol/L)

15.05 ± 0.43

20.48 ± 5.23

WBC (× 109/L)

7.31 ± 0.16

7.62 ± 0.22

Neutrophils (×109/L)

5.23 ± 0.16

5.70 ± 0.22

Hemoglobin (g/L)

127.66 ± 1.69

126.96 ± 1.71

platelets (× 109/L)

229.10 ± 4.34

241.23 ± 6.63

CRP (mg/L)

21.81 ± 1.73

29.81 ± 2.61

PT (S)

16.04 ± 1.22

13.90 ± 0.74

APTT (S)

38.83 ± 1.38

35.58 ± 1.15

ALT (IU/L)

22.27 ± 0.91

21.48 ± 1.39

AST (IU/L)

26.54 ± 0.73

26.52 ± 1.20

  1. SBP systolic blood pressure, DBP diastolic blood pressure, SCLC small-cell lung carcinoma, COPD Chronic obstructive pulmonary disease, CHD coronary heart disease, TC total cholesterol, HDLC high density lipoprotein cholesterol, LDLC low density lipoprotein cholesterol, Apo apolipoprotein, WBC white blood cell, CRP C-reactive protein, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase