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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells

Fig. 4

Chymostatin and aliskiren maintained HK2 cells proliferation after PA treatment. a Proliferating cells are labeled with EdU (shows as the red positive) and cell nuclei are marked with DAPI (shows as the blue positive). The proliferation of HK2 cells was decreased after PA treatment compared with control, which was prevented by combination treatment with chymostatin and aliskiren. b The ratio of EdU-positive cells and total cells are used for analyzingthe relative growth rate. Representative results of three independent experiments are shown. CTL, controls; PA, palmitic acid treatment group; PA + CMT, palmitic acid plus chymostatin treatment; PA + Ali, palmitic acid plus aliskiren treatment; PA + CA + Ali, palmitic acid plus chymostatin and aliskiren treatment. * p < 0.05 compared with controls; # p < 0.05 compared with PA

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