Skip to main content

Table 6 Quantitative Effect of the gene score (risk allele) on biochemical traits, expressed as the beta effect (Standard error)

From: Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs

Parameter

β (SE)

p-value

p-value (adjusted for BMI)

TC (mmol/L)

0.168 (0.018)

3.01 × 10−17

1.12 × 10−10

TG (mmol/L)

0.090 (0.021)

2.71 × 10−3

1 × 10−1

HDLC (mmol/L)

−0.498 (0.039)

5.4 × 10−43

1.1 × 10−13

LDLC (mmol/L)

0.211 (0.029)

1.11 × 10−21

2.5 × 10−6

  1. The beta effect means the rise or fall in the selected trait per each risk allele increase. For example, for TC, a beta effect of 0.168 means that with each risk allele increase, the serum total cholesterol increases by 0.168 mmol/L.
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X