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Table 2 Comparison of Association of Individual SNPs and Gene Score with Obesity

From: Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs

Gene

SNP/GS

OR

p-value

GRB14

rs3923113

0.903

0.598

ST6GAL1

rs16861329

0.586

0.007

VPS26A

rs1802295

1.366

0.087

AP3S2

rs2028299

1.351

0.094

HNF4A

rs4812829

1.429

0.047

HMG20A

rs7178572

1.149

0.373

FABP2

Ala54Thr

1.379

0.045

LEP

G2548A

1.560

0.006

LEPR

Gln223Arg

1.379

0.045

FTO

rs1121980

1.346

0.089

Gene Score

1.175

0.0001

  1. The OR for the individual SNPs and the p-values indicate a marginal or no association with the outcome, however, when a gene score is used, the association with obesity becomes significant