Fig. 4

The composition of major intestinal microflora 2 weeks after Rosuvastatin treatment. a, Shannon analysis showed that the diversity of intestinal microflora from Group Antibiotic+Statin are significantly reduced compared to Group Statin and Water. b, Principle component analysis of the major composition of the intestinal microflora from different groups. The major population of intestinal microflora are remarkably changed upon the antibiotic treatment. c, Bray analysis of the major intestinal microflora from different groups. d, Lactobacillu is remarkably diminished upon the antibiotic treatment. e, Bifidobacterium is remarkably reduced upon the antibiotic treatment. The comparisons were performed using one-way ANOVA with Tukey’s multiple comparisons test. The data were presented as mean ± sem. *, p < 0.01; **, p < 0.05; ***, p < 0.001