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Table 2 Image analysis of matrix and sintered formulations

From: Effect of lipid and cellulose based matrix former on the release of highly soluble drug from extruded/spheronized, sintered and compacted pellets

Formulations

Area

Perimeter

Circumference

Feret Diameter

Aspect Ratio

Sphericity

F00

37,632

688.009

0.999

226.883

1.066

0.938

F0

30,484

618.894

1

202.988

1.052

0.951

F1

15,453

545.717

0.652

187.182

1.764

0.567

F2

18,006

561.265

0.718

202.41

1.928

0.519

F3

23,448

689.207

0.62

254.167

2.517

0.397

F4

13,765

502.334

0.685

177.505

1.646

0.608

F5

13,502

413.119

0.994

142.79

1.174

0.852

F6

8957

336.15

0.996

113.745

1.119

0.894

F7

12,079

389.557

1

127.883

1.048

0.954

F8

9258

340.863

1

111.018

1.027

0.973

F9

11,516

380.133

1

123.045

1.017

0.984

F10

13,208

444.987

0.838

158.028

1.528

0.655

F11

11,243

413.361

0.827

140.46

1.268

0.789

F12

16,118

516.55

0.759

179.477

1.689

0.592

F13

17,678

575.009

0.672

229.369

2.364

0.423

F14

18,515

592.862

0.662

231.683

2.483

0.403

F15

26,743

656.143

0.781

258.606

1.883

0.531

F16

25,230

626.354

0.808

234.196

1.694

0.59

F17

11,738

384.845

0.996

131.746

1.149

0.87

F18

8371

326.726

0.985

117.516

1.286

0.778

F19

12,975

457.073

0.78

154.311

1.412

0.708

F20

9916

412.01

0.734

123.794

1.605

0.752

F21

6586

287.456

1

94.895

1.756

0.647

F22

6643

289.027

0.999

95.885

1.067

0.937

F23

6988

301.593

0.965

114.438

1.458

0.686

F24

7010

296.881

0.999

98.858

1.078

0.928

F25

7952

317.301

0.993

110.653

1.196

0.836

F26

11,208

375.42

0.999

123.794

1.059

0.944

F27

8952

337.721

0.986

120.702

1.263

0.792

F28

8906

334.58

1

108.005

1.008

0.992

F29

9001

336.15

1

108.268

1

1

F30

13,271

408.407

1

131.947

1.014

0.986

F31

11,703

383.274

1

124.04

1.017

0.983

F32

9238

340.863

0.999

114.739

1.106

0.904

F33

13,901

417.832

1

135.831

1.029

0.971

F34

11,872

386.416

0.999

127.012

1.051

0.951

F35

8175

320.442

1

105.802

1.061

0.943