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Table 2 Estimation of the standardized difference means of related indictors with CI 95% between the intervention and placebo groups

From: The effects of inositol supplementation on lipid profiles among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials

Variables

Number of study

Standardized mean difference

CI 95%

Heterogeneity

I-squared (%)

Q

P-value

Triglycerides

Intervention group (after vs. before)

12

− 1.84

− 2.62, − 1.06

95.6

248.31

< 0.001

Placebo group (after vs. before)

12

− 0.17

− 0.39, 0.05

53.9

23.84

0.01

Intervention group vs. placebo group

12

− 1.24

− 1.84, − 0.64

93.2

161.55

< 0.001

Total cholesterol

Intervention group (after vs. before)

11

− 1.40

− 2.11, − 0.69

94.7

189.67

< 0.001

Placebo group (after vs. before)

11

0.22

−0.17, 0.61

84.7

65.30

< 0.001

Intervention group vs. placebo group

11

−1.19

− 1.83, −0.55

93.6

156.53

< 0.001

LDL-cholesterol

Intervention group (after vs. before)

5

−1.28

−2.37, −0.18

94.4

71.88

< 0.001

Placebo group (after vs. before)

5

0.23

0.02, 0.44

0.00

3.13

0.53

Intervention group vs. placebo group

5

−1.31

−2.23, −0.39

92.2

51.00

< 0.001

HDL-cholesterol

Intervention group (after vs. before)

10

0.37

−0.13, 0.87

90.7

96.93

< 0.001

Placebo group (after vs. before)

10

−0.02

− 0.20, 0.15

27.2

12.37

0.19

Intervention group vs. placebo group

10

0.20

−0.27, 0.67

89.4

84.52

< 0.001