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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: LpA-II:B:C:D:E: a new immunochemically-defined acute phase lipoprotein in humans

Fig. 4

Endotoxin alters distribution of ApoE among plasma lipoproteins. The concentration of (a) apoE in plasma, (b) apoE associated with HDL (ApoE heparin soluble [HS]), (c) apoE associated with apoB-containing lipoproteins (ApoE-heparin precipitate [HP]) was measured at baseline and for 8 h after an intravenous dose of endotoxin (closed circles, n = 11) or saline (open circles, n = 4). (d) Changes in distribution of apoE in heparin soluble (HS) and heparin precipitate (HP) is expressed as the apoE HS/apoE HP ratio. Data were analyzed by 2-way repeated measures ANOVA (time x LPS treatment) with Dunnett’s posthoc analysis for time points compared to baseline in saline (+; p < 0.05) or LPS (#; p < 0.05). A Sidak’s multiple comparison test used to compare treatment groups at a single time point (*p < 0.05)

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