Association of the APOA1 rs964184 SNP and serum lipid traits in the Chinese Maonan and Han populations

Table 1 Comparison of demographic, lifestyle characteristics and serum lipid levels between the Maonan and Han populations

Parameter	Maonan	Han	t (χ²)	P
Number	867	820
Gender (Male/female)	329/538	306/514	0.071	0.790
Age (year)	57.71 ± 14.74	56.34 ± 15.63	0.672	0.513
Height (cm)	152.90 ± 11.90	153.99 ± 7.71	−1.425	0.154
Weight (kg)	52.50 ± 10.96	53.86 ± 9.20	−1.936	0.053
Body mass index (kg/m²)	22.21 ± 3.91	22.65 ± 3.11	−1.712	0.087
Waist circumference (cm)	75.86 ± 10.22	75.40 ± 7.89	0.730	0.466
Cigarette smoking [n(%)]
Non-smoker	698(80.46)	617(75.25)	7.019	0.030
≤ 20 cigarettes per day	148(17.08)	181(22.04)
> 20 cigarettes per day	21(2.46)	22(2.71)
Alcohol consumption [n (%)]
Non-drinker	707(81.60)	662(80.68)	2.351	0.309
≤ 25 g per day	80(9.20)	92(11.19)
> 25 g per day	80(9.20)	66(8.13)
Systolic blood pressure (mmHg)	135.73 ± 26.01	130.46 ± 19.72	3.353	0.001
Diastolic blood pressure (mmHg)	83.57 ± 13.61	82.52 ± 11.61	1.144	0.253
Pulse pressure (mmHg)	52.15 ± 17.91	47.95 ± 15.47	3.611	0.000
Glucose (mmol/L)	5.69 ± 2.03	5.97 ± 1.61	−2.045	0.041
Total cholesterol (mmol/L)	4.97 ± 1.08	4.97 ± 1.03	0.058	0.953
Triglyceride (mmol/L)	1.22(0.85)	1.1(0.88)	−2.632	0.009
HDL-C (mmol/L)	1.62 ± 0.40	1.69 ± 0.42	−2.286	0.023
LDL-C (mmol/L)	2.83 ± 0.81	2.88 ± 0.87	−0.878	0.380
Apolipoprotein (Apo) A1 (g/L)	1.39 ± 0.32	1.30 ± 0.25	4.219	0.000
ApoB (g/L)	0.87 ± 0.20	0.85 ± 0.20	1.603	0.109
ApoA1/ApoB	1.66 ± 0.61	1.61 ± 0.50	1.208	0.227

HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between the two ethnic groups was determined by the Wilcoxon-Mann-Whitney test

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