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Table 2 Relationship between risk factors and different nature plaques in CAHD patients compared using ANOVA (n = 484)

From: Low LPA gene kringle IV-2 repeat copy number association with elevated lipoprotein (a) concentration as an independent risk factor of coronary atherosclerotic heart disease in the Chinese Han population

 

Soft plaque

n = 259

Calcified plaque

n = 129

Mixed plaque

n = 96

P value

P1 value

P2 value

P3 value

Age (years)

61.37 ± 9.13

63.41 ± 8.72

64.38 ± 8.88

0.010

0.045

0.006

0.446

Sex (male), n (%)

145(56%)

64(49.6%)

68(70.8%)

0.020b

/

/

/

Total cholesterol (mmol/L)

4.90 ± 1.11

4.68 ± 1.01

4.62 ± 1.04

0.045

0.080

0.028

0.640

LDL-cholesterol (mmol/L)

3.27 ± 1.01

3.08 ± 0.88

2.93 ± 0.99

0.009

0.080

0.003

0.266

HDL-cholesterol (mmol/L)

1.32 ± 0.38

1.42 ± 0.67

1.24 ± 0.43

0.076

0.110

0.275

0.026

Non-HDL cholesterol (mmol/L)

3.58 ± 1.11

3.27 ± 1.36

3.37 ± 1.05

0.041

0.017

0.139

0.498

Triglycerides (mmol/L)

2.00 ± 1.26

1.80 ± 1.04

2.20 ± 1.52

0.076

0.168

0.181

0.023

Apo(B) (g/L)

1.12 ± 0.34

1.06 ± 0.38

1.06 ± 0.31

0.178

0.128

0.144

0.983

Lp(a)-mass, (mg/L)a

200(69–383)

166(77–293)

149(64–279)

0.025

0.049

0.018

0.662

Lp(a)-particle, (nmol/L)a

21.5(5.3–52)

18.6(5.3–43.1)

17.1(7.6–28.01)

0.006

0.038

0.003

0.391

KIV-2 copy numbers (copies)

14.31 ± 6.94

13.84 ± 5.25

13.87 ± 4.20

0.768

0.543

0.587

0.979

HbA1C (%)

6.10 ± 1.08

6.12 ± 0.89

6.18 ± 0.99

0.783

0.848

0.485

0.657

HS-CRP (mg/L)a

0.91(0.45–1.79)

0.86(0.43–1.88)

0.92(0.45–2.52)

0.515

0.292

0.456

0.814

  1. Notice: P value calculated among three groups; P1 value compared between soft and calcified plaque; P2 value compared between soft and mixed plaque; P3 value compared between calcified and mixed plaque
  2. aResults shown as mean ± SD or median (interquartile range)
  3. bResults compared using the chi-square test