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Table 1 Baseline clinical characteristics and risk factors in patients with CAHD and without

From: Low LPA gene kringle IV-2 repeat copy number association with elevated lipoprotein (a) concentration as an independent risk factor of coronary atherosclerotic heart disease in the Chinese Han population

 

CAHD group

n = 484 (54.8%)

Non-CAHD group

n = 400 (45.2%)

t/χ2

P value

Age(y)

62.46 ± 9.06

56.39 ± 9.57

−9.405c

0.000

Sex (male), n (%)

277(57.2%)

170(42.5%)

19.635b

0.000

Diabetes mellitus,n(%)

108(22.3%)

28(7.0%)

39.451b

0.000

Total cholesterol (mmol/L)

4.79 ± 1.08

4.84 ± 0.98

0.710

0.478

LDL-C (mmol/L)

3.15 ± 0.99

3.15 ± 0.89

0.016

0.988

HDL-C (mmol/L)

1.33 ± 0.59

1.42 ± 0.41

2.661c

0.008

non-HDL-C (mmol/L)

3.46 ± 1.17

3.42 ± 0.94

−0.593

0.553

Triglycerides (mmol/L)

1.99 ± 1.27

1.83 ± 1.27

−1.801

0.072

Apo(B) (g/L)

1.09 ± 0.35

1.05 ± 0.31

−1.847

0.065

Lp(a)-mass (mg/L)a

181(69–346)

130(66–287)

−3.121c

0.002

Lp(a)-particle (nmol/L)a

19.1(8.8–44.9)

14.4(7.6–32.3)

−2.543c

0.011

KIV-2 copy numbers (copies)

14.11 ± 6.13

15.14 ± 7.11

2.205c

0.040

HbA1C (%)

6.12 ± 1.02

5.83 ± 0 .66

−4.824c

0.000

hs-CRP (mg/L)a

0.91(0.44–2.02)

0.68(0.38–1.62)

−2.967c

0.003

  1. Continuous variables are expressed as mean ± SD or a median (interquartile range) and compared using ‘t’ test
  2. bCategorical variables are expressed a numbers (%) and compared using the chi-square test
  3. cCompared with control group, P < 0.05