Table 4 Predictors for Cardiovascular events according to Cox’s proportional hazard analysis
From: Effects of statin therapy on chronic kidney disease patients with coronary artery disease
Variables | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
CKD versus CKD + CAD | 0.5 | (0.27–0.68) | < 0.001 | 0.46 | (0.25–0.59) | < 0.001 |
Age (years) | 1.32 | (1.21–1.93) | < 0.001 | 1.1 | (0.95–1.04) | 0.078 |
Male (versus female) | 0.76 | (0.57–1.15) | 0.545 | – | ||
Hypertension | 1.61 | (1.21–2.01) | < 0.01 | 1.16 | (0.95–1.67) | 0.071 |
Diabetes mellitus | 1.24 | (0.87–1.72) | 0.291 | – | ||
Smoking | 1.43 | (1.33–1.81) | < 0.01 | 1.41 | (1.09–2.11) | 0.009 |
Myocardial infarction | 1.18 | (1.06–1.89) | 0.048 | 1.03 | (0.91–1.35) | 0.121 |
Angina pectoris | 1.07 | (0.67–1.46) | 0.32 | – | ||
Stroke | 1.53 | (0.97–3.16) | 0.221 | – | ||
Calcium-channel blocker | 1.27 | (0.76–1.50) | 0.322 | – | ||
ACEI | 0.97 | (0.85–1.30) | 0.976 | – | ||
ARB | 0.89 | (0.63–1.28) | 0.514 | – | ||
β-blocker | 1.42 | (1.12–1.89) | < 0.01 | 1.11 | (0.72–1.61) | 0.55 |
Loop diuretic | 1.09 | (0.61–1.76) | 0.488 | – | ||
Aspirin | 1.98 | (1.56–3.97) | < 0.01 | 1.32 | (0.68–1.99) | 0.601 |
Triglycerides (mmol/l) | 1.12 | (0.72–1.81) | 0.78 | – | ||
Total cholesterol (mmol/l) | 1.07 | (0.87–1.75) | 0.64 | – | ||
LDL-C (mmol/l) | 1.12 | (1.07–1.62) | < 0.001 | 1.05 | (1.01–1.25) | 0.011 |
HDL-C (mmol/l) | 0.69 | (0.46–1.21) | 0.222 | – | ||
Glucose (mmol/l) | 1.23 | (0.96–1.91) | 0.52 | – | ||
HbA1c (%) | 0.96 | (0.68–1.69) | 0.771 | – | ||
SBP (mmHg) | 0.97 | (0.90–1.18) | 0.078 | – | ||
DBP (mmHg) | 1.08 | (0.97–1.39) | 0.56 | – | ||
Long-term statins | 0.22 | (0.19–0.57) | < 0.001 | 0.27 | (0.21–0.41) | < 0.001 |