Table 1 Important regulatory genes and pathways related to lipid metabolism in comparison of control group and SNE group
Pathway | P-value | Pathway ID | Genes |
|---|---|---|---|
Steroid hormone biosynthesis | 0.05007 | gga00140 | CYP17A1; CYP1B1 |
Steroid biosynthesis | 0.07212 | gga00100 | LIPA |
Ether lipid metabolism | 0.08339 | gga00565 | LPCAT1; PLA2G4A |
alpha-Linolenic acid metabolism | 0.10632 | gga00592 | PLA2G4A |
Linoleic acid metabolism | 0.13425 | gga00591 | PLA2G4A |
beta-Alanine metabolism | 0.16359 | gga00410 | ALDH1A3 |
Arachidonic acid metabolism | 0.34997 | gga00590 | PLA2G4A |
Glycerophospholipid metabolism | 0.41918 | gga00564 | LPCAT1; PLA2G4A |
PPAR signaling pathway | 0.49544 | gga03320 | PLIN2 |
Insulin resistance | 0.50696 | gga04931 | PIK3R5; PRKCB |
Adipocytokine signaling pathway | 0.52206 | gga04920 | TNFRSF1B |
Insulin signaling pathway | 0.84921 | gga04910 | PIK3R5 |