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Table 5 Comparison of Mean lipid parameter values across GRS quartiles

From: GWAS implicated risk variants in different genes contribute additively to increase the risk of coronary artery disease (CAD) in the Pakistani subjects

Parameter

Q1

Q2

Q3

β-effect

p-value

TC (mg/dL)

192.6 ± 4.3

197.2 ± 2.4

196.6 ± 3.3

0.049

0.676

TG (mg/dL)

160.2 ± 6.1

202.4 ± 3.2

212.4 ± 6.1

0.064

0.022

HDL-C (mg/dL)

53.8 ± 1.5

53.1 ± 1.8

48.3 ± 3.1

−0.064

0.536

LDL-C (mg/dL)

93.9 ± 2.7

93.6 ± 1.5

104.8 ± 1.3

0.020

0.449

  1. Q1: GRS 0–4, Q2: GRS 5–8, Q3: GRS 9–12
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Lipids in Health and Disease

ISSN: 1476-511X