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Table 6 Combined effects of the rs619586 and rs664589 polymorphisms on CAD risk

From: Association of polymorphisms in MALAT1 with risk of coronary atherosclerotic heart disease in a Chinese population

Combined genotypes

Controls (%)

CAD (%)

OR (95% CI)

P value †

rs619586AA + rs664589CC

359 (63.88)

344 (67.72)

1.00

 

rs619586AA + rs664589CG/GG

45 (8.01)

66 (12.99)

1.53 (1.02–2.30)

0.04

rs619586AG /GG + rs664589CC

51 (9.07)

14 (2.76)

0.29 (0.16–0.53)

<  0.001

rs619586AG /GG + rs664589CG/GG

107 (19.04)

84 (16.54)

0.82 (0.59–1.13)

0.22

  1. CAD coronary atherosclerotic heart disease, OR odds ratio, CI confidence interval
  2. †P value was adjusted for multiple comparisons by Bonferroni correction
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Lipids in Health and Disease

ISSN: 1476-511X