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Table 3 Genotype frequencies of CONNEXIN37 gene polymorphisms in cases and controls and their associations with ischemic stroke

From: Polymorphism of CONNEXIN37 gene is a risk factor for ischemic stroke in Han Chinese population

Genotype

IS group (n)

Control group (n)

OR (95%CI)a

P value

Adjusted OR (95%CI)b

P value

rs1764391

 CC

217

242

    

 CT

160

101

1.767 (1.297-2.407)

0.000

1.748 (1.149-2.658)

0.009

 TT

8

19

0.470 (0.201-1.094)

0.080

0.173 (0.052-0.580)

0.004

 Recessive

  

0.383 (0.166-0.886)

0.025

0.138 (0.042-0.459)

0.001

 Additive

  

1.262 (0.976-1.632)

0.076

1.066 (0.754-1.508)

0.718

 Dominant

  

1.561 (1.160-2.102)

0.003

1.428 (0.955-2.134)

0.082

rs1764390

 AA

76

100

    

 AG

223

196

1.497 (1.050-2.134)

0.026

1.522 (0.937-2.473)

0.090

 GG

86

66

1.715 (1.106-2.657)

0.016

1.278 (0.697-2.344)

0.428

 Recessive

  

1.290 (0.901-1.847)

0.164

0.950 (0.577-1.565)

0.841

 Additive

  

1.317 (1.058-1.639)

0.014

1.149 (0.851-1.552)

0.364

 Dominant

  

1.552 (1.104-2.182)

0.011

1.456 (0.913-2.321)

0.115

  1. aUnivariate analysis
  2. bAdjusted OR (Covariates: age, systolic blood pressure, diastolic blood pressure, body mass index, smoking, drinking history, triglycerides, HDL cholesterol, LDL cholesterol, fasting blood glucose)