Table 2 Myeloperoxidase level, inflammatory markers, lipid, lipoprotein parameters and lipid and lipoprotein ratios in SCAD patients and the reference group (median (minimum-maximum)
MPO < 200 ng/ml, n = 26 | MPO200–300 ng/ml n = 26 | MPO > 300 ng/ml n = 15 | MPO ng/ml n = 67 | Controls n = 15 | |
|---|---|---|---|---|---|
TC (mmol/L) | 4.50 (3.73–5.02) | 3.91 (3.41–4.64) | 3.99 (3.03–7.74) | 4.33 (3.03–7.74) | 4.87 (2.79–5.18) |
LDL-C (mmol/L) | 2.48 (1.96–3.09) | 2.30 (3.95–3.10) | 2.20 (1.32–5.49) | 2.38 (1.96–5.49) | 3.03 (1.10–3.99) |
HDL-C (mmol/L) | 1.08 (0.93–1.32)** | 1.08 (1.01–1.42)** | 0.95 (0.60–1.42)*** | 1.07 (0.60–1.42)** | 1.55 (1.14–2.30) |
TG (mmol/L) | 1.88 (1.58–2.73)* | 1.67 (0.93–2.12)* | 1.72 (0.93–3.91)* | 1.75 (0.93–3.91)* | 1.06 (0.34–2.70) |
nonHDL-C (mmol/L) | 1.51 (1.16–1.71) | 1.19 (0.93–1.45) | 1.32 (1.07–1.70) | 1.40 (0.93–1.71) | 1.06 (0.34–2.70) |
apoAI (g/L) | 1.45 (1.20–1.51) | 1.39 (1.29–1.60)* | 1.29 (1.15–1.75)**↑ | 1.38 (1.15–1.75)* | 1.57 (1.35–1.99) |
apoAII(g/L) | 0.29 (0.27–0.32) | 0.28 (0.25–0.34) | 0.29 (0.25–0.34) | 0.29 (0.25–0.34) | 0.32 (0.29–0.38) |
ApoB (g/L) | 0.93 (0.864–1.26)* | 0.90 (0.67–1.12)* | 0.96 (0.63–1.16)* | 0.94 (0.63–1.25)* | 0.70 (0.41–1.17) |
LpPLA2 (ng/ml) | 101 (86–185) | 98 (67–164) | 112 (79–126) | 103 (67–185) | 72.4 (32–172.1) |
TC/HDL-C | 4.15 (3.39–5.36)* | 3.59 (1.58–5.80) | 4.10 (3.39–4.77)* | 3.79 (1.58–5.80) | 3.13 (2.60–3.71) |
LDL-C/HDL-C | 2.26 (2.09–3.13) | 2.14 (1.25–2.59) | 2.28 (1.76–2.81) | 2.25 (1.25–2.81) | 1.95 (1.31–2.40) |
TG/HDL-C | 3.90 (2.04–6.19)* | 3.52 (1.79–3.9)* | 3.90 (1.65–4.76)* | 3.48 (1.79–6.19)* | 1.60 (1.12–3.02) |
apoB/apoAI | 0.62 (0.60–0.90)* | 0.65 (0.46–0.84)* | 0.75 (0.55–0.86)** | 0.69 (0.55–0.90)** | 0.46 (0.27–0.64) |
HDL-C/apoAI | 0.30 (0.27–0.36)** | 0.31 (0.29–0.38)** | 0.29 (0.26–0.37)**↑ | 0.31 (0.26–0.38)** | 0.39 (0.32–0.46) |
MPO ng/ml | 138 (72.4–176) | 230 (203–263)** | 350 (303–393)*** | 229 (72.4–393)** | 90.0 (49–153) |
hsCRP (μg/ml) | 0.141 (0.086–0.28)** | 0.157 (0.086–0.38)** | 0.21 (0.086–1.38)***↑ | 0.152 (0.086–1.38)** | 0.09 (0.02–0.5) |
TNF-alfa (pg/ml) | 5.23 (4.8–8.3)*** | 5.31 (4.18–6.25)*** | 5.80 (4.86–6.61)*** | 5.35 (4.18–8.3)*** | 1.20 (0.60–1.21) |
IL-6 (pg/ml) | 1.74 (0.84–3.51)** | 2.54 (1.42–3.50)*** | 3.02 (2.36–3.80)*** | 2.64 (0.84–3.80)*** | 0.40 (0.20–0.83) |
MPO/apoAI | 0.95 (0.61–1.10)* | 1.65(1.46–1.88)** | 2.72 (2.05–2.92)***↑ | 1.67 (0.61–2.92)** | O.55 (0.26–2.53) |
MPO/HDL-C | 2.51 (1.84–4.14)* | 5.41 (3.95–5.94)** | 8.51 (5.60–9.15)***↑ | 5.23 (1.84–5.94)** | 1.48 (0.63–4.51) |