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Table 2 Characteristics of H.E.L.P.-apheresis. The characteristics of H.E.L.P.-apheresis in patients treated in this study (n = 6) are compared to theory (calculated values) and literature

From: Lipoprotein turnover and possible remnant accumulation in preeclampsia: insights from the Freiburg Preeclampsia H.E.L.P.-apheresis study

 

Preeclampsia measureda

(Freiburg)

Preeclampsia measured

Wang et al. [17]

Preeclampsia calculatedb

H.E.L.P. literaturea

Plasma treated [ml]

2566 ± 361

2566

2500–3000 [19, 20]

ApoB reduction [%]

−47 ± 14%

− 59 ± 5

- 63% [31], − 54% [21]

LDL-cholesterol reduction [%]

−43 ± 17%

−44%

−59 ± 5

−67% [22], − 53% [21]

HDL-cholesterol reduction [%]

−7 ± 5%

−15%

− 15 ± 2

− 15% [22], − 12% [21]

Triglycerides reduction [%]

−42 ± 14%

−41%

−41% [22], − 55% [21], − 60% [19]

ApoA1 reduction [%]

−17 ± 5%

− 16% [21]

Total plasma volume [ml]

2827 ± 225c

 

2827c

2638 ± 414 (non-pregnant) [50]

3216 ± 168 (normotensive pregnancy) [29]

Plasmaflow [ml/min]

25 ± 3

 

20–30 [20]

Duration of apheresis [min]

123 ± 17

 

100–150 [20]

  1. aAs occurring or worsening edema during therapy interferes with calculating the plasma volume, only data from each patient’s first apheresis were considered; bTheoretical reduction was calculated in consideration of the plasma volume and treated plasma volume according to Eq. 1