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Table 5 Effect of the DOCK7–ANGPTL3 SNPs on angiographic severity of CAD

From: DOCK7-ANGPTL3 SNPs and their haplotypes with serum lipid levels and the risk of coronary artery disease and ischemic stroke

SNP/Genotype

Rs1748195

Rs12563308

 

OR (95% CI)

P

 

OR (95% CI)

P

Codominant

CC

1

 

TT

1

 
 

CG

1.40 (0.94–2.08)

0.142

TC

0.89 (0.46–1.70)

0.859

 

GG

1.71 (0.81–3.61)

 

CC

0.57 (0.05–6.73)

 

Dominant

CC

1

 

TT

1

 
 

CG/GG

1.45 (1.07–2.11)

0.017

CT/CC

0.86 (0.46–1.63)

0.660

Recessive

CC/CG

1

 

TT/CT

1

 
 

GG

1.49 (0.72–3.10)

0.271

CC

0.58 (0.05–6.80)

0.671

Log–additve

C

1

 

T

1

 
 

G

1.35 (1.09–1.82)

0.013

C

0.86 (0.48–1.54)

0.614

  1. Based to different number of main vessel stenosis by coronary angiography in CAD patients, Polytomous Logistic Regression for Ordinal Response was employeed to assess the severity, and environmental factors like sex, age, BMI, cigarette smoking, alcohol consumption, hypertension, hyperlipidemia were adjusted. A P < 0.025 was considered statistically significant after Bonferroni correction